Assessment of the efficacy, tolerance, and regenerative properties of Cicaplast Baume B5+ Balm — results of an observational study
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Abstract
Background: The skin, as the body’s largest organ, is prone to various forms of damage, ranging from minor abrasions to complex dermatological conditions. Effective treatments are essential to promote skin regeneration while minimizing infection and scarring risks. This study evaluates the regenerative properties of Cicaplast Baume B5+ Balm (La Roche-Posay), a topical treatment with 5% panthenol (vitamin B5) and madecassoside, across a range of skin conditions.
Material and methods: A total of 364 participants, who underwent recent dermatological procedures or experienced conditions like contact dermatitis or actinic keratosis, were recruited. Participants applied the balm twice daily for 14 days, and data on wound healing, symptom reduction, and patient satisfaction were collected via questionnaires.
Results: The results demonstrated significant improvement in skin healing in 84% of patients, with reductions in erythema (84.5%), desquamation (69.5%), and fissures (54%). Both patients and doctors reported high satisfaction, with over 96% rating the balm’s effectiveness as “good” or “excellent”. Almost all patients (98.4%) were satisfied with its soothing effects and ease of application. While the study confirms the balm’s efficacy in promoting skin recovery, the lack of a control group and the short follow-up period are notable limitations.
Conclusions: Overall, Cicaplast Baume B5+ Balm proves to be an effective treatment for enhancing skin regeneration and alleviating discomfort across various dermatological conditions.
Keywords: dermocosmeticsCicaplast Baume B5+skin barrier
References
- Heise R, Schmitt L, Huth L, et al. Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial. Cutan Ocul Toxicol. 2019; 38(3): 274–278.
- Liu M, Dai Y, Li Y, et al. Madecassoside isolated from Centella asiatica herbs facilitates burn wound healing in mice. Planta Med. 2008; 74(8): 809–815.
- Bandopadhyay S, Mandal S, Ghorai M, et al. Therapeutic properties and pharmacological activities of asiaticoside and madecassoside: a review. J Cell Mol Med. 2023; 27(5): 593–608.
- Li W, Yu Q, Shen Z, et al. Effects of a cream containing madecassoside, 5% panthenol, and copper-zinc-manganese on improving postlaser resurfacing wound healing: a split-face, randomized trial. Dermatol Ther. 2020; 33(4): e13533.
- Zhang Q. Effect of cream containing asiaticoside and 5% panthenol on skin repair after non-ablative fractional laser surgery. Chin J Med Aesth. 2022; 28(1): 9–12.
- Pavlačková J, Egner P, Sedláček T, et al. In vivo efficacy and properties of semisolid formulations containing panthenol. J Cosmet Dermatol. 2019; 18(1): 346–354.
- Gorski J, Proksch E, Baron JM, et al. Dexpanthenol in wound healing after medical and cosmetic interventions (postprocedure wound healing). Pharmaceuticals (Basel). 2020; 13(7): 138.
- Tan S, Bhattamisra S, Chellappan D, et al. Actions and therapeutic potential of madecassoside and other major constituents of centella asiatica: a review. Appl Sci. 2021; 11(18): 8475.
- Brandt S. The clinical effects of zinc as a topical or oral agent on the clinical response and pathophysiologic mechanisms of acne: a systematic review of the literature. J Drugs Dermatol. 2013; 12(5): 542–545.
- Moskovicz V, Gross A, Mizrahi B. Extrinsic factors shaping the skin microbiome. Microorganisms. 2020; 8(7): 1023.
- Berger A, Regueiro C, Hijal T, et al. Interest of supportive and barrier protective skin care products in the daily prevention and treatment of cutaneous toxicity during radiotherapy for breast cancer. Breast Cancer (Auckl). 2018; 12: 1178223417752772.
- Araviiskaia E, Layton AM, Estebaranz JL, et al. The synergy between pharmacological regimens and dermocosmetics and its impact on adherence in acne treatment. Dermatol Res Pract. 2022; 2022: 3644720.
