Online first
Research paper
Published online: 2024-05-29

open access

Page views 59
Article views/downloads 41
Get Citation

Connect on Social Media

Connect on Social Media

The application of repeated whole-body cryotherapy in atopic dermatitis and its impact on Staphylococcus aureus colonization — pilot study

Magdalena Kępińska-Szyszkowska1, Anna Misiorek1, Monika Kapińska-Mrowiecka2, Karolina Reiprich2

Abstract

Introduction: Staphylococcus aureus can directly penetrate the stratum corneum and epidermis, which explains why this microorganism can disrupt the immune homeostasis of the skin and potentially influence skin diseases. Whole-body cryotherapy (W-BC) is one of the methods used in cryotherapy. It is well known that exposure to extremely low temperatures in the human body induces metabolic, hormonal, and thermoregulatory reactions. The study aimed to investigate whether repeated whole-body cryotherapy treatments would have an impact on the colonization of Staphylococcus aureus in individuals with atopic dermatitis (AD).

Methods: Fourteen adults with a mean age of 32 ± 10.8 and mild to moderate AD (mean of SCORAD index 36.5 points) were enrolled in the study. Whole-body cryotherapy comprised a total of 15 treatments, once a day.

Results: In the following research, it has been observed that whole-body cryotherapy treatments have an impact on the colonization of Staphylococcus aureus on the skin of patients with AD. It would be beneficial to include a larger sample size of AD patients, including both those receiving W-BC treatments and those who do not.

Conclusions: Based on the following research, W-BC can be considered an effective adjunctive method in the treatment of AD.

Article available in PDF format

View PDF Download PDF file

References

  1. Weidinger S, Novak N. Atopic dermatitis revisited. Allergy. 2014; 69(1): 1–2.
  2. Sroka-Tomaszewska J, Trzeciak M. Molecular mechanisms of atopic dermatitis pathogenesis. Int J Mol Sci. 2021; 22(8): 4130.
  3. Williams MR, Nakatsuji T, Sanford JA, et al. Staphylococcus aureus induces increased serine protease activity in keratinocytes. J Invest Dermatol. 2017; 137(2): 377–384.
  4. Blicharz L, Rudnicka L, Samochocki Z. Staphylococcus aureus: an underestimated factor in the pathogenesis of atopic dermatitis? Adv Dermatol Allergol. 2019; 36(1): 11–17.
  5. Skopowska A, Ciechanowska K, Szymańska J. Zastosowanie niskich temperatur w wybranych jednostkach chorobowych. Rehabilitacja w praktyce. 2015; 1: 37–39.
  6. Rymaszewska J, Pawik M. Czy krioterapia ogólnoustrojowa staje się formą terapii? Fam Med Prim Care Rev. 2013; 15: 247–250.
  7. Sieroń A, Cieślar G. Zastosowanie zimna w medycynie — kriochirurgia i krioterapia: podstawy teoretyczne, efekty biologiczne, zastosowania kliniczne. Wydawnictwo Alfa Medica Press, Bielsko Biała 2003.
  8. Kepinska-Szyszkowska M, Misiorek A, Kapinska-Mrowiecka M, et al. Assessment of the influence systemic cryotherapy exerts on chosen skin scores of patients with atopic dermatitis: pilot study. Biomed Res Int. 2020; 7: 5279642.
  9. Misiorek A, Szyszkowska-Kępińska M. Evaluation of the influence of whole-body cryotherapy on selected skin parameters in healthy individuals: Pilot study. Cryobiology. 2021; 100: 77–80.
  10. Hanifin J, Rajka G. Diagnostic features of atopic dermatitis. Acta Dermato-Venereologica. 1980; 60: 44–47.
  11. Chiu LS, Chow VC, Ling JM, et al. Staphylococcus aureus carriage in the anterior nares of close contacts of patients with atopic dermatitis. Arch Dermatol. 2010; 146(7): 748–752.
  12. Teległów A, Marchewka J, Tabarowski Z, et al. Comparison of selected morphological, rheological and biochemical parameters of winter swimmers' blood at the end of one winter swimming season and at the beginning of another. Folia Biol (Krakow). 2015; 63(3): 221–228.
  13. Westerlund T, Oksa J, Smolander J, et al. Thermal responses during and after whole-body cryotherapy (−110°C). J Therm Biol. 2003; 28(8): 601–608.
  14. Cholewka A, Stanek A, Sieroń A, et al. Thermography study of skin response due to whole-body cryotherapy. Skin Res Technol. 2012; 18(2): 180–187.