open access

Vol 80, No 4 (2021)
Original article
Submitted: 2020-08-24
Accepted: 2020-10-04
Published online: 2020-10-27
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Liver anatomy, intrahepatic vascular and biliary branching system of the mole rat (Spalax leucodon)

I. Nešić1, N. Krstić2, N. Djelić3, M. Zdravković4, B. Tošković4, M. Djordjević1, M. Blagojević1
DOI: 10.5603/FM.a2020.0132
·
Pubmed: 33124033
·
Folia Morphol 2021;80(4):888-894.
Affiliations
  1. Department of Anatomy, Faculty of Veterinary Medicine, University of Belgrade, Serbia
  2. Department of Radiology and Radiation Hygiene, Faculty of Veterinary Medicine, University of Belgrade, Serbia
  3. Department of Biology, Faculty of Veterinary Medicine, University of Belgrade, Serbia
  4. Faculty of Medicine, University of Belgrade, Medical Centre Bežanijska Kosa, Belgrade, Serbia

open access

Vol 80, No 4 (2021)
ORIGINAL ARTICLES
Submitted: 2020-08-24
Accepted: 2020-10-04
Published online: 2020-10-27

Abstract

Background: There are many studies on the morphology of the liver and its blood vessels in experimental animals, but such studies are lacking in the mole rat (Spalax leucodon). The aim of this paper was a detailed basic study on the topography, morphology, vascular and biliary branching systems of the liver in the mole rat.
Materials and methods: Coloured gelatine and mixture of coloured lead oxide and linseed oil were injection contrast masses used to obtain vascular and biliary branching pattern in the liver. It was revealed that the liver of the mole rat had five lobes (left, quadrate, right medial, right lateral and caudate lobes).
Results: The left, undivided lobe was the largest lobe of the liver. The quadrate lobe was divided into two components by a deep notch. The gallbladder, of cylindrical shape, was present and attached to the quadrate lobe. The common bile duct was formed by the union of the left and right hepatic ducts. The pancreatic duct joined the common bile duct before it entered the duodenum. In the present study, only the right medial lobe and quadrate lobe always showed a single lobar artery, portal and hepatic veins. The left lobe showed four lobar arteries, portal and hepatic veins. The caudate lobe with its two processes and the right lateral and medial lobes had different arterial and portal blood supply as well as hepatic and biliary drainage of these lobes. The intrahepatic branches of the proper hepatic artery ran parallel to the branches of the common portal vein in the same lobes of the liver.
Conclusions: The results of this study are significant for comparative studies among different species of rodents and other experimental animals. Morphology, vasculature and biliary tract of the liver in the mole rat were similar to that of other experimental animals and identified differences may be related to the adaptation to the mode of life and diet of this rodent.

Abstract

Background: There are many studies on the morphology of the liver and its blood vessels in experimental animals, but such studies are lacking in the mole rat (Spalax leucodon). The aim of this paper was a detailed basic study on the topography, morphology, vascular and biliary branching systems of the liver in the mole rat.
Materials and methods: Coloured gelatine and mixture of coloured lead oxide and linseed oil were injection contrast masses used to obtain vascular and biliary branching pattern in the liver. It was revealed that the liver of the mole rat had five lobes (left, quadrate, right medial, right lateral and caudate lobes).
Results: The left, undivided lobe was the largest lobe of the liver. The quadrate lobe was divided into two components by a deep notch. The gallbladder, of cylindrical shape, was present and attached to the quadrate lobe. The common bile duct was formed by the union of the left and right hepatic ducts. The pancreatic duct joined the common bile duct before it entered the duodenum. In the present study, only the right medial lobe and quadrate lobe always showed a single lobar artery, portal and hepatic veins. The left lobe showed four lobar arteries, portal and hepatic veins. The caudate lobe with its two processes and the right lateral and medial lobes had different arterial and portal blood supply as well as hepatic and biliary drainage of these lobes. The intrahepatic branches of the proper hepatic artery ran parallel to the branches of the common portal vein in the same lobes of the liver.
Conclusions: The results of this study are significant for comparative studies among different species of rodents and other experimental animals. Morphology, vasculature and biliary tract of the liver in the mole rat were similar to that of other experimental animals and identified differences may be related to the adaptation to the mode of life and diet of this rodent.

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Keywords

liver, a. hepatica propria, v. portae, vv. hepaticae, bile ducts

About this article
Title

Liver anatomy, intrahepatic vascular and biliary branching system of the mole rat (Spalax leucodon)

Journal

Folia Morphologica

Issue

Vol 80, No 4 (2021)

Article type

Original article

Pages

888-894

Published online

2020-10-27

Page views

2434

Article views/downloads

1221

DOI

10.5603/FM.a2020.0132

Pubmed

33124033

Bibliographic record

Folia Morphol 2021;80(4):888-894.

Keywords

liver
a. hepatica propria
v. portae
vv. hepaticae
bile ducts

Authors

I. Nešić
N. Krstić
N. Djelić
M. Zdravković
B. Tošković
M. Djordjević
M. Blagojević

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