open access

Ahead of Print
Original article
Submitted: 2023-07-19
Accepted: 2023-10-18
Published online: 2023-10-30
Get Citation

Computational modeling of the cephalic arch with jugulocephalic vein variant predicts hemodynamic profiles in patients with brachiocephalic fistula

Jiaoran Li1, Junrui Chen2, Xuetao Zhu3, Kaining Huo4, Xianhao Shao5, Menglin Cong3, Zhen Liu4, Zhenzhong Li4, Weiming Yue1
·
Pubmed: 37957941
Affiliations
  1. Department of Thoracic Surgery, Qilu Hospital, Shandong University, Jinan, Shandong Province, China
  2. Department of Marine Engineering, Haerbin Institute of Technology, Weihai, Shandong Province, China
  3. Department of Orthopaedics, Qilu Hospital, Shandong University, Jinan, Shandong Province, China
  4. Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong Province, China
  5. Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China

open access

Ahead of Print
ORIGINAL ARTICLES
Submitted: 2023-07-19
Accepted: 2023-10-18
Published online: 2023-10-30

Abstract

Background: The cephalic vein is often used in for arteriovenous fistula creation; however, the cephalic vein variation is common. This study will propose new theoretical explanations for a new discovered variation of cephalic vein draining into external jugular vein with “T-junction” shape by means of 3D computational hemodynamic modeling, which may provide reference for clinical practice.

Methods: The precise measurements were conducted for the variant right cephalic vein draining into external jugular vein and for a normal right cephalic vein as a control. After processing the anatomical data, 3D geometrical model was reconstructed. Then, the influent field inside the variant jugulocephalic vein was mathematically modeled to get a detailed description of hemodynamic environment.

Results: The anatomical parameters of the “T-junction” jugulocephalic vein variant were much more different from the normal right cephalic vein. The wall shear stress of variant cephalic vein at the corresponding position was higher and changed more rapidly than that of normal cephalic vein. The shear rate contour lines are disordered in several areas of the variant cephalic vein, indicating that the hemodynamic parameters in these areas are unstable. The hemodynamic characteristics at the confluence of the variant cephalic vein are more complex, with more areas where hemodynamic parameters are disrupted.

Conclusions: The variation of cephalic arch in a “T-junction” with external jugular vein largely altered the fluid dynamics, especially in hemodialysis patients with brachiocephalic fistula in terms of the simulating flow in 3D computational model. This computational model provides hemodynamic profiles for stabilizing or modulating fluid dynamics in patients with jugulocephalic vein variant after brachiocephalic fistula.

Abstract

Background: The cephalic vein is often used in for arteriovenous fistula creation; however, the cephalic vein variation is common. This study will propose new theoretical explanations for a new discovered variation of cephalic vein draining into external jugular vein with “T-junction” shape by means of 3D computational hemodynamic modeling, which may provide reference for clinical practice.

Methods: The precise measurements were conducted for the variant right cephalic vein draining into external jugular vein and for a normal right cephalic vein as a control. After processing the anatomical data, 3D geometrical model was reconstructed. Then, the influent field inside the variant jugulocephalic vein was mathematically modeled to get a detailed description of hemodynamic environment.

Results: The anatomical parameters of the “T-junction” jugulocephalic vein variant were much more different from the normal right cephalic vein. The wall shear stress of variant cephalic vein at the corresponding position was higher and changed more rapidly than that of normal cephalic vein. The shear rate contour lines are disordered in several areas of the variant cephalic vein, indicating that the hemodynamic parameters in these areas are unstable. The hemodynamic characteristics at the confluence of the variant cephalic vein are more complex, with more areas where hemodynamic parameters are disrupted.

Conclusions: The variation of cephalic arch in a “T-junction” with external jugular vein largely altered the fluid dynamics, especially in hemodialysis patients with brachiocephalic fistula in terms of the simulating flow in 3D computational model. This computational model provides hemodynamic profiles for stabilizing or modulating fluid dynamics in patients with jugulocephalic vein variant after brachiocephalic fistula.

Get Citation

Keywords

computational modeling; jugulocephalic vein variant; cephalic arch; brachiocephalic fistula; hemodynamics

Supp./Additional Files (4)
Supplement data
Download
10MB
Video 1:The isopleth of wall shear rate in variant cephalic vein.This video shows the distribution and alterations of isopleth of wall shear rate in the model of variant cephalic vein and external jugular vein.The contour lines defined at 100 lines.
Download
4MB
Video 2: The streamline of variant cephalic vein. This video shows the velocity alterations in the model of variant cephalic vein and external jugular vein with serial sections at YZ plane.
Download
5MB
Video 3: The vortex intensity in variant cephalic vein. This video shows the range of intensity from lower to higher with color. The color arrows show the vortex intensity and direction.
Download
4MB
About this article
Title

Computational modeling of the cephalic arch with jugulocephalic vein variant predicts hemodynamic profiles in patients with brachiocephalic fistula

Journal

Folia Morphologica

Issue

Ahead of Print

Article type

Original article

Published online

2023-10-30

Page views

182

Article views/downloads

120

DOI

10.5603/fm.96565

Pubmed

37957941

Keywords

computational modeling
jugulocephalic vein variant
cephalic arch
brachiocephalic fistula
hemodynamics

Authors

Jiaoran Li
Junrui Chen
Xuetao Zhu
Kaining Huo
Xianhao Shao
Menglin Cong
Zhen Liu
Zhenzhong Li
Weiming Yue

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By VM Media Group sp. z o.o., Grupa Via Medica, Świętokrzyska 73, 80–180 Gdańsk, Poland

tel.: +48 58 320 94 94, faks: +48 58 320 94 60, e-mail: viamedica@viamedica.pl