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Computational modeling of the cephalic arch with jugulocephalic vein variant predicts hemodynamic profiles in patients with brachiocephalic fistula
, 2, 3, 4, 5, 3, 4, 4, 1
Affiliations- Department of Thoracic Surgery, Qilu Hospital, Shandong University, Jinan, Shandong Province, China
- Department of Marine Engineering, Haerbin Institute of Technology, Weihai, Shandong Province, China
- Department of Orthopaedics, Qilu Hospital, Shandong University, Jinan, Shandong Province, China
- Department of Anatomy and Neurobiology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong Province, China
- Department of Orthopaedics, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China
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Abstract
Background: The cephalic vein is often used in for arteriovenous fistula creation; however, the cephalic vein variation is common. This study will propose new theoretical explanations for a new discovered variation of cephalic vein draining into external jugular vein with “T-junction” shape by means of 3D computational hemodynamic modeling, which may provide reference for clinical practice.
Methods: The precise measurements were conducted for the variant right cephalic vein draining into external jugular vein and for a normal right cephalic vein as a control. After processing the anatomical data, 3D geometrical model was reconstructed. Then, the influent field inside the variant jugulocephalic vein was mathematically modeled to get a detailed description of hemodynamic environment.
Results: The anatomical parameters of the “T-junction” jugulocephalic vein variant were much more different from the normal right cephalic vein. The wall shear stress of variant cephalic vein at the corresponding position was higher and changed more rapidly than that of normal cephalic vein. The shear rate contour lines are disordered in several areas of the variant cephalic vein, indicating that the hemodynamic parameters in these areas are unstable. The hemodynamic characteristics at the confluence of the variant cephalic vein are more complex, with more areas where hemodynamic parameters are disrupted.
Conclusions: The variation of cephalic arch in a “T-junction” with external jugular vein largely altered the fluid dynamics, especially in hemodialysis patients with brachiocephalic fistula in terms of the simulating flow in 3D computational model. This computational model provides hemodynamic profiles for stabilizing or modulating fluid dynamics in patients with jugulocephalic vein variant after brachiocephalic fistula.
Abstract
Background: The cephalic vein is often used in for arteriovenous fistula creation; however, the cephalic vein variation is common. This study will propose new theoretical explanations for a new discovered variation of cephalic vein draining into external jugular vein with “T-junction” shape by means of 3D computational hemodynamic modeling, which may provide reference for clinical practice.
Methods: The precise measurements were conducted for the variant right cephalic vein draining into external jugular vein and for a normal right cephalic vein as a control. After processing the anatomical data, 3D geometrical model was reconstructed. Then, the influent field inside the variant jugulocephalic vein was mathematically modeled to get a detailed description of hemodynamic environment.
Results: The anatomical parameters of the “T-junction” jugulocephalic vein variant were much more different from the normal right cephalic vein. The wall shear stress of variant cephalic vein at the corresponding position was higher and changed more rapidly than that of normal cephalic vein. The shear rate contour lines are disordered in several areas of the variant cephalic vein, indicating that the hemodynamic parameters in these areas are unstable. The hemodynamic characteristics at the confluence of the variant cephalic vein are more complex, with more areas where hemodynamic parameters are disrupted.
Conclusions: The variation of cephalic arch in a “T-junction” with external jugular vein largely altered the fluid dynamics, especially in hemodialysis patients with brachiocephalic fistula in terms of the simulating flow in 3D computational model. This computational model provides hemodynamic profiles for stabilizing or modulating fluid dynamics in patients with jugulocephalic vein variant after brachiocephalic fistula.
Keywords
computational modeling; jugulocephalic vein variant; cephalic arch; brachiocephalic fistula; hemodynamics
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About this articleTitle
Computational modeling of the cephalic arch with jugulocephalic vein variant predicts hemodynamic profiles in patients with brachiocephalic fistula
Journal
Issue
Article type
Original article
Published online
2023-10-30
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126
DOI
Pubmed
Keywords
computational modeling
jugulocephalic vein variant
cephalic arch
brachiocephalic fistula
hemodynamics
Authors
Jiaoran Li
Junrui Chen
Xuetao Zhu
Kaining Huo
Xianhao Shao
Menglin Cong
Zhen Liu
Zhenzhong Li
Weiming Yue
