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ORIGINAL ARTICLES
Published online: 2018-08-09
Submitted: 2018-04-25
Accepted: 2018-06-24
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Can constant light exposure affect the thyroid gland in prepubertal male albino rats? Histological and ultrastructural study

Fayza A. Abdel Gawad, Ehab Abdel Aziz El-Shaarawy, Shreif F. Arsanyos, Tarek I. Abd El-Galil, Ghada N. Awes
DOI: 10.5603/FM.a2018.0073
·
Pubmed: 30106459

open access

Ahead of Print
ORIGINAL ARTICLES
Published online: 2018-08-09
Submitted: 2018-04-25
Accepted: 2018-06-24

Abstract

Background: Through scientific literature, there is evidence that light affects thyroid function in human, mice and rabbits. Constant light and sleep deprivation is also used as a form of human torture, as it has impact on cognitive performances. The present work was conducted to study the effect of constant light for short and long periods on the thyroid gland in the prepubertal male albino rats.

Material and methods: A total of 30 prepubertal male albino rats were used. The rats separated under three groups, group I (control), group II were those rats put under steady encompassing light  (24 h/day, light intensity of 600 lux) for four weeks. Group III were the rats maintained in constant light for three months. The rat thyroid gland was subjected to histological and ultrastructural examination. 

Results: The rats exposed to light for long durations showed disturbed architecture; the follicles exhibited back to back arrangement (signs of hypertrophy with hyperplasia), lined by multiple layers of follicular cells or were lined by vacuolated cells. Few thyroid follicles were exhibited cystic hyperplasia. Congested blood capillaries were demonstrated between the follicles.

Conclusions: It can be concluded that the short period of constant light for one month had more or less no apparent effect on thyroid gland tissues while longer light periods for three months brought on detrimental outcomes on the thyroid gland structure of male albino rats.

Abstract

Background: Through scientific literature, there is evidence that light affects thyroid function in human, mice and rabbits. Constant light and sleep deprivation is also used as a form of human torture, as it has impact on cognitive performances. The present work was conducted to study the effect of constant light for short and long periods on the thyroid gland in the prepubertal male albino rats.

Material and methods: A total of 30 prepubertal male albino rats were used. The rats separated under three groups, group I (control), group II were those rats put under steady encompassing light  (24 h/day, light intensity of 600 lux) for four weeks. Group III were the rats maintained in constant light for three months. The rat thyroid gland was subjected to histological and ultrastructural examination. 

Results: The rats exposed to light for long durations showed disturbed architecture; the follicles exhibited back to back arrangement (signs of hypertrophy with hyperplasia), lined by multiple layers of follicular cells or were lined by vacuolated cells. Few thyroid follicles were exhibited cystic hyperplasia. Congested blood capillaries were demonstrated between the follicles.

Conclusions: It can be concluded that the short period of constant light for one month had more or less no apparent effect on thyroid gland tissues while longer light periods for three months brought on detrimental outcomes on the thyroid gland structure of male albino rats.

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Keywords

constant light, thyroid gland histological, prepubertal rats and thyroid gland ultrastructural

About this article
Title

Can constant light exposure affect the thyroid gland in prepubertal male albino rats? Histological and ultrastructural study

Journal

Folia Morphologica

Issue

Ahead of Print

Published online

2018-08-09

DOI

10.5603/FM.a2018.0073

Pubmed

30106459

Keywords

constant light
thyroid gland histological
prepubertal rats and thyroid gland ultrastructural

Authors

Fayza A. Abdel Gawad
Ehab Abdel Aziz El-Shaarawy
Shreif F. Arsanyos
Tarek I. Abd El-Galil
Ghada N. Awes

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