open access

Vol 75, No 3 (2016)
REVIEW ARTICLES
Published online: 2016-01-19
Submitted: 2015-09-20
Accepted: 2015-11-10
Get Citation

The impact of type 1 diabetes on the development of the craniofacial mineralised tissues (bones and teeth): literature review

R. Chałas, O. Rudzka, I. Wójcik-Chęcińska, M. Vodanović
DOI: 10.5603/FM.a2016.0001
·
Folia Morphol 2016;75(3):275-280.

open access

Vol 75, No 3 (2016)
REVIEW ARTICLES
Published online: 2016-01-19
Submitted: 2015-09-20
Accepted: 2015-11-10

Abstract

Background: There are many reports on the impact of diabetes on periodontium as well as the state of organs in diabetics; however, there is little research on the impact of the disease on morphological and anatomical changes in the mineralised tissues like teeth and craniofacial bones. The aim of this study was to present a review of literature on morphological and anatomical changes of mineralised tissues in the course of type 1 diabetes.

Materials and methods: A review of PubMed database was made using the keywords: morphological changes, anatomical changes, enamel hypoplasia, type 1 diabetes, induced diabetes and the names of individual anatomical and morphological structures of the teeth.

Results: The analysis of experimental studies have shown that in induced type 1 diabetes in rats there is a substantial reduction in the thickness of the enamel and dentin, compared with the control group. The changes in the content of indivi­dual minerals in the tissues of the tooth have been shown — a decrease in the concentration of calcium and fluoride ions and an increase in the concentration of magnesium. In a study conducted on embryos of rats born of diabetic dams, defects were observed in enamel organ, which can cause delayed enamel hypo­plasia. Literature analysis revealed morphological disorders also in some clinical cases of patients with type 1 diabetes.

Conclusions: Type 1 diabetes mellitus as a metabolic disorder may affect changes in the structure of mineralised tissues, thereby increasing their susceptibility to caries development and orthognathic disorders.

Abstract

Background: There are many reports on the impact of diabetes on periodontium as well as the state of organs in diabetics; however, there is little research on the impact of the disease on morphological and anatomical changes in the mineralised tissues like teeth and craniofacial bones. The aim of this study was to present a review of literature on morphological and anatomical changes of mineralised tissues in the course of type 1 diabetes.

Materials and methods: A review of PubMed database was made using the keywords: morphological changes, anatomical changes, enamel hypoplasia, type 1 diabetes, induced diabetes and the names of individual anatomical and morphological structures of the teeth.

Results: The analysis of experimental studies have shown that in induced type 1 diabetes in rats there is a substantial reduction in the thickness of the enamel and dentin, compared with the control group. The changes in the content of indivi­dual minerals in the tissues of the tooth have been shown — a decrease in the concentration of calcium and fluoride ions and an increase in the concentration of magnesium. In a study conducted on embryos of rats born of diabetic dams, defects were observed in enamel organ, which can cause delayed enamel hypo­plasia. Literature analysis revealed morphological disorders also in some clinical cases of patients with type 1 diabetes.

Conclusions: Type 1 diabetes mellitus as a metabolic disorder may affect changes in the structure of mineralised tissues, thereby increasing their susceptibility to caries development and orthognathic disorders.

Get Citation

Keywords

diabetes type 1, tooth morphology, mineralised tissues

About this article
Title

The impact of type 1 diabetes on the development of the craniofacial mineralised tissues (bones and teeth): literature review

Journal

Folia Morphologica

Issue

Vol 75, No 3 (2016)

Pages

275-280

Published online

2016-01-19

DOI

10.5603/FM.a2016.0001

Bibliographic record

Folia Morphol 2016;75(3):275-280.

Keywords

diabetes type 1
tooth morphology
mineralised tissues

Authors

R. Chałas
O. Rudzka
I. Wójcik-Chęcińska
M. Vodanović

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