open access

Vol 59, No 4 (2000)
ORIGINAL ARTICLES
Published online: 2000-08-02
Submitted: 2012-02-06
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Substance-P of neural cells in human trigeminal ganglion

Maria Prośba-Mackiewicz, Albina Żółtowska, Jerzy Dziewiątkowski
Folia Morphol 2000;59(4):327-331.

open access

Vol 59, No 4 (2000)
ORIGINAL ARTICLES
Published online: 2000-08-02
Submitted: 2012-02-06

Abstract

Expression of substance-P in human neurons of trigeminal ganglia has been investigated by immunohistochemistry and morphometry. These neurons constituted 12.8% to 32.6% of the total neuronal population in the trigeminal ganglia. Substance-P positive granulations were concentrated around the nucleus, distributed focally in neuroplasm or dispersed over the neuroplasm. Morphometric analysis has indicated the presence of three populations of SP-positive cells: small, medium-sized and large.
The results suggest a functional differentiation on the level of the first neurons of the afferent path of the stomatognatic system. Substance-P is likely to play a role in the transmission not only of nociceptive impulses but also of those involved in the mechano-functional stimulation of system activities.

Abstract

Expression of substance-P in human neurons of trigeminal ganglia has been investigated by immunohistochemistry and morphometry. These neurons constituted 12.8% to 32.6% of the total neuronal population in the trigeminal ganglia. Substance-P positive granulations were concentrated around the nucleus, distributed focally in neuroplasm or dispersed over the neuroplasm. Morphometric analysis has indicated the presence of three populations of SP-positive cells: small, medium-sized and large.
The results suggest a functional differentiation on the level of the first neurons of the afferent path of the stomatognatic system. Substance-P is likely to play a role in the transmission not only of nociceptive impulses but also of those involved in the mechano-functional stimulation of system activities.
Get Citation

Keywords

substance-P; human trigeminal ganglia; neurons; immunohistochemistry; morphometry

About this article
Title

Substance-P of neural cells in human trigeminal ganglion

Journal

Folia Morphologica

Issue

Vol 59, No 4 (2000)

Pages

327-331

Published online

2000-08-02

Bibliographic record

Folia Morphol 2000;59(4):327-331.

Keywords

substance-P
human trigeminal ganglia
neurons
immunohistochemistry
morphometry

Authors

Maria Prośba-Mackiewicz
Albina Żółtowska
Jerzy Dziewiątkowski

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