The structure of the cusps of valves in the human foetal great saphenous vein

Abstract

The study was performed on 110 great saphenous veins in human foetuses of both sexes aged 9 to 37 weeks. The earliest well-shaped valves were observed in foetuses aged 13 weeks. In these foetuses the number of valves varies from 2 to 7. Consecutive microscopic sections revealed that the developing valves at their origin present thickening of the endothelium which is continuous into the cusps of the valves. The bicuspid cusps are crescent-shaped and both surfaces are lined by endothelium.