open access

Vol 62, No 4 (2003)
Short Communications
Published online: 2003-09-05
Submitted: 2012-02-06
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Preliminary comparative immunocytochemical study of respiratory tract endocrine cells in certain rodents

Bogusław Sawicki, Irena Kasacka, Elżbieta Czykier, Barbara Piłat-Marcinkiewicz, Maciej Zabel
Folia Morphol 2003;62(4):411-413.

open access

Vol 62, No 4 (2003)
Short Communications
Published online: 2003-09-05
Submitted: 2012-02-06

Abstract

Studies were performed on 3 species belonging to two families: Microtidae (7 common voles and 7 pine voles), and Muridae - 10 Wistar rats. In rodents the airways endocrine cells (ECs) are localised in the epithelium lining the larynx, trachea, bronchi, bronchioles and lung. CGRP-, synaptophysin (SY)-, calcitonin (CT)-, neuron-specific enolase (NSE)- and chromogranin A (CA)- immunoreactivity were nearly totally co-localised in ECs. In the region of the tracheo-larynx junction, CGRP- and NSE-positive cells were observed in the epithelium of the glands. It is surmised that some of the CGRP-positive ECs do not generate CT and CA, for the most part in ECs. In Microtidae ECs were more abundant than in the rat and were found even in the epithelium lining of the inside larynx in the transition region before the trachea.

Abstract

Studies were performed on 3 species belonging to two families: Microtidae (7 common voles and 7 pine voles), and Muridae - 10 Wistar rats. In rodents the airways endocrine cells (ECs) are localised in the epithelium lining the larynx, trachea, bronchi, bronchioles and lung. CGRP-, synaptophysin (SY)-, calcitonin (CT)-, neuron-specific enolase (NSE)- and chromogranin A (CA)- immunoreactivity were nearly totally co-localised in ECs. In the region of the tracheo-larynx junction, CGRP- and NSE-positive cells were observed in the epithelium of the glands. It is surmised that some of the CGRP-positive ECs do not generate CT and CA, for the most part in ECs. In Microtidae ECs were more abundant than in the rat and were found even in the epithelium lining of the inside larynx in the transition region before the trachea.
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Keywords

rodents endocrine cells; larynx; trachea; lung; immunocytochemistry

About this article
Title

Preliminary comparative immunocytochemical study of respiratory tract endocrine cells in certain rodents

Journal

Folia Morphologica

Issue

Vol 62, No 4 (2003)

Pages

411-413

Published online

2003-09-05

Bibliographic record

Folia Morphol 2003;62(4):411-413.

Keywords

rodents endocrine cells
larynx
trachea
lung
immunocytochemistry

Authors

Bogusław Sawicki
Irena Kasacka
Elżbieta Czykier
Barbara Piłat-Marcinkiewicz
Maciej Zabel

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