Vol 63, No 2 (2004)
Short communication
Published online: 2004-03-12
Exercise-induced apoptosis in renal tubular cells of the rat
Folia Morphol 2004;63(2):213-216.
Abstract
A number of studies have shown that acute physical exercise is associated with
the induction of apoptosis not only in skeletal muscle but also in many distant
organs. One of the pathogenic agents responsible for exercise-induced damage
in many tissues is the generation of oxygen free radicals. The aim of the present
study was to examine the influence of exercise-induced oxidative stress on the
rat kidney. The analysis was performed on the kidneys of rats subjected to treadmill
running until exhaustion. Our results demonstrated that acute exercise led
to apoptotic damage of the renal distal tubular cells, although this was not
a result of oxidative stress.
Keywords: apoptosisexercisekidneyoxidative stress