open access

Vol 63, No 2 (2004)
SHORT COMMUNICATIONS
Published online: 2004-03-12
Submitted: 2012-02-06
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Exercise-induced apoptosis in renal tubular cells of the rat

Podhorska-Okołów M, Dzięgiel P, Murawska-Ciałowicz E, Krajewska B, Ciesielska U, Jethon Z, Zabel M
Folia Morphol 2004;63(2):213-216.

open access

Vol 63, No 2 (2004)
SHORT COMMUNICATIONS
Published online: 2004-03-12
Submitted: 2012-02-06

Abstract

A number of studies have shown that acute physical exercise is associated with the induction of apoptosis not only in skeletal muscle but also in many distant organs. One of the pathogenic agents responsible for exercise-induced damage in many tissues is the generation of oxygen free radicals. The aim of the present study was to examine the influence of exercise-induced oxidative stress on the rat kidney. The analysis was performed on the kidneys of rats subjected to treadmill running until exhaustion. Our results demonstrated that acute exercise led to apoptotic damage of the renal distal tubular cells, although this was not a result of oxidative stress.

Abstract

A number of studies have shown that acute physical exercise is associated with the induction of apoptosis not only in skeletal muscle but also in many distant organs. One of the pathogenic agents responsible for exercise-induced damage in many tissues is the generation of oxygen free radicals. The aim of the present study was to examine the influence of exercise-induced oxidative stress on the rat kidney. The analysis was performed on the kidneys of rats subjected to treadmill running until exhaustion. Our results demonstrated that acute exercise led to apoptotic damage of the renal distal tubular cells, although this was not a result of oxidative stress.
Get Citation

Keywords

apoptosis; exercise; kidney; oxidative stress

About this article
Title

Exercise-induced apoptosis in renal tubular cells of the rat

Journal

Folia Morphologica

Issue

Vol 63, No 2 (2004)

Pages

213-216

Published online

2004-03-12

Bibliographic record

Folia Morphol 2004;63(2):213-216.

Keywords

apoptosis
exercise
kidney
oxidative stress

Authors

Podhorska-Okołów M
Dzięgiel P
Murawska-Ciałowicz E
Krajewska B
Ciesielska U
Jethon Z
Zabel M

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