open access

Vol 63, No 2 (2004)
SHORT COMMUNICATIONS
Published online: 2004-03-12
Submitted: 2012-02-06
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A morphometric study of nucleolar organiser regions in cervical intraepithelial neoplasia

Terlikowski S, Dzięcioł J, Mazurek A, Sulkowski S, Boroń R, Oniszczuk M, Lejmanowicz K
Folia Morphol 2004;63(2):209-212.

open access

Vol 63, No 2 (2004)
SHORT COMMUNICATIONS
Published online: 2004-03-12
Submitted: 2012-02-06

Abstract

The study sought a correlation between the number of AgNOR granules and the degree of cervical intraepithelial neoplasia (CIN). Thirty-five sections (5 normal, 10 CIN1, 10 CIN2 and 10 CIN3) were subjected to retrospective analysis. The percentage of cells with 1, 2, 3, 4 and more AgNORs was calculated and the number of granules per 100 cells was counted. The number of cells containing single granules decreases. However, the number increases with CIN level when the cells contain 4 and more AgNORs. The number of granules per 100 cells also increases with the degree of CIN. It can be thus concluded that the number of cells with 4 and more AgNOR granules can serve as a CIN differentiation exponent.

Abstract

The study sought a correlation between the number of AgNOR granules and the degree of cervical intraepithelial neoplasia (CIN). Thirty-five sections (5 normal, 10 CIN1, 10 CIN2 and 10 CIN3) were subjected to retrospective analysis. The percentage of cells with 1, 2, 3, 4 and more AgNORs was calculated and the number of granules per 100 cells was counted. The number of cells containing single granules decreases. However, the number increases with CIN level when the cells contain 4 and more AgNORs. The number of granules per 100 cells also increases with the degree of CIN. It can be thus concluded that the number of cells with 4 and more AgNOR granules can serve as a CIN differentiation exponent.
Get Citation

Keywords

cervical intraepithelial neoplasia; argyrophilic nucleolar organiser regions

About this article
Title

A morphometric study of nucleolar organiser regions in cervical intraepithelial neoplasia

Journal

Folia Morphologica

Issue

Vol 63, No 2 (2004)

Pages

209-212

Published online

2004-03-12

Bibliographic record

Folia Morphol 2004;63(2):209-212.

Keywords

cervical intraepithelial neoplasia
argyrophilic nucleolar organiser regions

Authors

Terlikowski S
Dzięcioł J
Mazurek A
Sulkowski S
Boroń R
Oniszczuk M
Lejmanowicz K

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