open access

Vol 63, No 4 (2004)
ORIGINAL ARTICLES
Published online: 2004-09-16
Submitted: 2012-02-06
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Do the asymmetry and the size of the structures of the temporal lobe persist in early stages of schizophrenia?

Joanna M. Moryś, Jerzy Dziewiątkowski, Barbara Bobek-Billewicz, Ilona Ratajczak, Olgierd Narkiewicz, Janusz Moryś
Folia Morphol 2004;63(4):401-405.

open access

Vol 63, No 4 (2004)
ORIGINAL ARTICLES
Published online: 2004-09-16
Submitted: 2012-02-06

Abstract

A total of 14 patients of various ages diagnosed with schizophrenia and, as an age-matched control group, 12 healthy subjects were examined using the MRI method of neuro-imaging. The volume of the following structures was evaluated in the right and left hemispheres: the superior temporal gyrus, the basolateral temporal area (the region including the middle temporal gyrus, inferior temporal gyrus and fusiform gyrus), the parahippocampal gyrus, the hippocampal head, the amygdaloid body and the inferior horn of the lateral ventricle. In schizophrenia a significant increase in the volume of the amygdaloid body on both the left and right sides was observed. In the patients, as in the control group, we noticed significant asymmetry between the left and right sides in the volume of the structures studied. The left amygdaloid body was significantly larger than the right, whereas the left hippocampal head and the temporal horn of the lateral ventricle were smaller than the right. Our findings suggest that in the early stages of schizophrenia, despite the increased volume of the amygdaloid body, the asymmetry between the structures of the temporal lobe is still present. However, the changes observed in the temporal lobe could be related to the functional disturbances observed in this disease.

Abstract

A total of 14 patients of various ages diagnosed with schizophrenia and, as an age-matched control group, 12 healthy subjects were examined using the MRI method of neuro-imaging. The volume of the following structures was evaluated in the right and left hemispheres: the superior temporal gyrus, the basolateral temporal area (the region including the middle temporal gyrus, inferior temporal gyrus and fusiform gyrus), the parahippocampal gyrus, the hippocampal head, the amygdaloid body and the inferior horn of the lateral ventricle. In schizophrenia a significant increase in the volume of the amygdaloid body on both the left and right sides was observed. In the patients, as in the control group, we noticed significant asymmetry between the left and right sides in the volume of the structures studied. The left amygdaloid body was significantly larger than the right, whereas the left hippocampal head and the temporal horn of the lateral ventricle were smaller than the right. Our findings suggest that in the early stages of schizophrenia, despite the increased volume of the amygdaloid body, the asymmetry between the structures of the temporal lobe is still present. However, the changes observed in the temporal lobe could be related to the functional disturbances observed in this disease.
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Keywords

magnetic resonance imaging; volumetric study; temporal lobe; schizophrenia

About this article
Title

Do the asymmetry and the size of the structures of the temporal lobe persist in early stages of schizophrenia?

Journal

Folia Morphologica

Issue

Vol 63, No 4 (2004)

Pages

401-405

Published online

2004-09-16

Bibliographic record

Folia Morphol 2004;63(4):401-405.

Keywords

magnetic resonance imaging
volumetric study
temporal lobe
schizophrenia

Authors

Joanna M. Moryś
Jerzy Dziewiątkowski
Barbara Bobek-Billewicz
Ilona Ratajczak
Olgierd Narkiewicz
Janusz Moryś

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