Vol 63, No 4 (2004)
Original article
Submitted: 2012-02-06
Published online: 2004-09-16
Do the asymmetry and the size of the structures of the temporal lobe persist in early stages of schizophrenia?
Joanna M. Moryś, Jerzy Dziewiątkowski, Barbara Bobek-Billewicz, Ilona Ratajczak, Olgierd Narkiewicz, Janusz Moryś
Folia Morphol 2004;63(4):401-405.
Vol 63, No 4 (2004)
ORIGINAL ARTICLES
Submitted: 2012-02-06
Published online: 2004-09-16
Abstract
A total of 14 patients of various ages diagnosed with schizophrenia and, as an
age-matched control group, 12 healthy subjects were examined using the MRI
method of neuro-imaging. The volume of the following structures was evaluated
in the right and left hemispheres: the superior temporal gyrus, the basolateral
temporal area (the region including the middle temporal gyrus, inferior temporal
gyrus and fusiform gyrus), the parahippocampal gyrus, the hippocampal
head, the amygdaloid body and the inferior horn of the lateral ventricle.
In schizophrenia a significant increase in the volume of the amygdaloid body on
both the left and right sides was observed. In the patients, as in the control
group, we noticed significant asymmetry between the left and right sides in the
volume of the structures studied. The left amygdaloid body was significantly
larger than the right, whereas the left hippocampal head and the temporal horn
of the lateral ventricle were smaller than the right.
Our findings suggest that in the early stages of schizophrenia, despite the increased
volume of the amygdaloid body, the asymmetry between the structures
of the temporal lobe is still present. However, the changes observed in the temporal
lobe could be related to the functional disturbances observed in this disease.
Abstract
A total of 14 patients of various ages diagnosed with schizophrenia and, as an
age-matched control group, 12 healthy subjects were examined using the MRI
method of neuro-imaging. The volume of the following structures was evaluated
in the right and left hemispheres: the superior temporal gyrus, the basolateral
temporal area (the region including the middle temporal gyrus, inferior temporal
gyrus and fusiform gyrus), the parahippocampal gyrus, the hippocampal
head, the amygdaloid body and the inferior horn of the lateral ventricle.
In schizophrenia a significant increase in the volume of the amygdaloid body on
both the left and right sides was observed. In the patients, as in the control
group, we noticed significant asymmetry between the left and right sides in the
volume of the structures studied. The left amygdaloid body was significantly
larger than the right, whereas the left hippocampal head and the temporal horn
of the lateral ventricle were smaller than the right.
Our findings suggest that in the early stages of schizophrenia, despite the increased
volume of the amygdaloid body, the asymmetry between the structures
of the temporal lobe is still present. However, the changes observed in the temporal
lobe could be related to the functional disturbances observed in this disease.
Keywords
magnetic resonance imaging; volumetric study; temporal lobe; schizophrenia
Title
Do the asymmetry and the size of the structures of the temporal lobe persist in early stages of schizophrenia?
Journal
Folia Morphologica
Issue
Vol 63, No 4 (2004)
Article type
Original article
Pages
401-405
Published online
2004-09-16
Page views
624
Article views/downloads
1448
Bibliographic record
Folia Morphol 2004;63(4):401-405.
Keywords
magnetic resonance imaging
volumetric study
temporal lobe
schizophrenia
Authors
Joanna M. Moryś
Jerzy Dziewiątkowski
Barbara Bobek-Billewicz
Ilona Ratajczak
Olgierd Narkiewicz
Janusz Moryś