open access

Vol 65, No 2 (2006)
ORIGINAL ARTICLES
Published online: 2006-03-09
Submitted: 2012-02-06
Get Citation

The activity and immunoexpression of cathepsin D in rat male reproductive organs

F. Burdan, J. Szumiło, J. Dudka, A. Dąbrowski, R. Maciejewski, Z. Wójtowicz
Folia Morphol 2006;65(2):111-115.

open access

Vol 65, No 2 (2006)
ORIGINAL ARTICLES
Published online: 2006-03-09
Submitted: 2012-02-06

Abstract

Cathepsin D is a cysteine endopeptidase that belongs to the lysosomal enzyme family. The aim of the study was to evaluate the enzyme immunoexpression and activity in selected male genital organs in mature Wistar rats. The activity of cathepsin D was measured spectrophotometrically in homogenates of the testis, epididymis, seminal vesicle and prostate. Immunohistochemical staining was also performed in the ductus deferens. Enzyme activity was found in the following sequence: testis>epididymis>dorsal prostatic lobe>seminal vesicle>lateral prostatic lobe>ventral prostatic lobe. Although there were differences in enzyme activity between various organs of the male reproductive system, cathepsin D immunoreactivity was seen exclusively in the Sertoli and Leydig cells in the testis.

Abstract

Cathepsin D is a cysteine endopeptidase that belongs to the lysosomal enzyme family. The aim of the study was to evaluate the enzyme immunoexpression and activity in selected male genital organs in mature Wistar rats. The activity of cathepsin D was measured spectrophotometrically in homogenates of the testis, epididymis, seminal vesicle and prostate. Immunohistochemical staining was also performed in the ductus deferens. Enzyme activity was found in the following sequence: testis>epididymis>dorsal prostatic lobe>seminal vesicle>lateral prostatic lobe>ventral prostatic lobe. Although there were differences in enzyme activity between various organs of the male reproductive system, cathepsin D immunoreactivity was seen exclusively in the Sertoli and Leydig cells in the testis.
Get Citation

Keywords

cathepsin D; lysosomal enzyme; testis; epididymis; ductus deferens; seminal vesicle; prostate

About this article
Title

The activity and immunoexpression of cathepsin D in rat male reproductive organs

Journal

Folia Morphologica

Issue

Vol 65, No 2 (2006)

Pages

111-115

Published online

2006-03-09

Bibliographic record

Folia Morphol 2006;65(2):111-115.

Keywords

cathepsin D
lysosomal enzyme
testis
epididymis
ductus deferens
seminal vesicle
prostate

Authors

F. Burdan
J. Szumiło
J. Dudka
A. Dąbrowski
R. Maciejewski
Z. Wójtowicz

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By  "Via Medica sp. z o.o." sp.k., Świętokrzyska 73, 80–180 Gdańsk, Poland

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl