open access

Vol 69, No 1 (2010)
CASE REPORTS
Published online: 2010-03-09
Submitted: 2012-02-06
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Blue nevus of the endocervix

J. Szumiło, A. Patel, S. Patel, F. Burdan
Folia Morphol 2010;69(1):62-64.

open access

Vol 69, No 1 (2010)
CASE REPORTS
Published online: 2010-03-09
Submitted: 2012-02-06

Abstract

The mucosa of the uterine cervix is normally devoid of melanocytes; therefore, melanin-containing lesions are very rare in this site. A new case of a common blue nevus in the cervix of a 57-year-old woman is reported. The lesion was an incidental finding in a total hysterectomy specimen performed for atypical endometrial hyperplasia. Gross and histological examination revealed minute dark macula on the mucosa of the posterior aspect of the endocervical canal, composed of loose conglomerates of spindle-shaped and dendritic cells located superficially within the stroma, containing multiple brownish granules, which exhibited positive immunostaining for HMB45 and melan A. Although the blue nevi seem to be lesions of low clinical significance, they require careful differential diagnosis with malignant melanoma, especially in scanty endocervical curettage or cervical biopsy specimens.
Folia Morphol 2010; 69, 1: 62-64

Abstract

The mucosa of the uterine cervix is normally devoid of melanocytes; therefore, melanin-containing lesions are very rare in this site. A new case of a common blue nevus in the cervix of a 57-year-old woman is reported. The lesion was an incidental finding in a total hysterectomy specimen performed for atypical endometrial hyperplasia. Gross and histological examination revealed minute dark macula on the mucosa of the posterior aspect of the endocervical canal, composed of loose conglomerates of spindle-shaped and dendritic cells located superficially within the stroma, containing multiple brownish granules, which exhibited positive immunostaining for HMB45 and melan A. Although the blue nevi seem to be lesions of low clinical significance, they require careful differential diagnosis with malignant melanoma, especially in scanty endocervical curettage or cervical biopsy specimens.
Folia Morphol 2010; 69, 1: 62-64
Get Citation

Keywords

melanocytic nevus; melanocyte; uterine cervix

About this article
Title

Blue nevus of the endocervix

Journal

Folia Morphologica

Issue

Vol 69, No 1 (2010)

Pages

62-64

Published online

2010-03-09

Bibliographic record

Folia Morphol 2010;69(1):62-64.

Keywords

melanocytic nevus
melanocyte
uterine cervix

Authors

J. Szumiło
A. Patel
S. Patel
F. Burdan

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