Lower limb interosseous membrane in foetuses
, 34, 1, 5, 6, 1, 1, 78, 910, 1112
Abstract
Background: The leg interosseous membrane (LIM) stabilises the tibia and the fibula. These two bones articulate at the proximal and distal tibiofibular joints. In addition, the LIM is the place of attachment of tibialis anterior muscle, extensor digitorum longus muscle, fibularis tertius muscle (anatomical variant), tibialis posterior muscle and flexor hallucis longus muscle. The specific structure of the collagen fibre network of the LIM provides durability comprising collagenous fibres that are predominately projected longitudinally, obliquely, and often transversely. Materials and methods: 222 human foetuses (Male: 120, Female: 102) between 117 and 197 (median 177) days of foetal life were available for the study. The material derived from the foetal collection is stored in the Department of Human Morphology and Embryology, Division of Anatomy of the Medical University of Wroclaw. In this study, we assessed the variability of the foetal LIM using a novel dyeing technique to identify the LIM syndesmotic structure. Results: Overall, the study of the three types of interosseous fibres (transverse, oblique, longitudinal) of the right/left leg revealed that the fibres run in all three directions with frequencies approximating 60-70%. However, there were differences in the frequency of fibre directions and in the size of LIM between sexes. Conclusions: After consideration of the directions and size of fibres of LIM, parts of it can be used for reconstruction of the upper limb interosseous membrane. Sexually dimorphic features of the LIM in the studied material confirm the different dynamics of lower limb growth in each sex.
Keywords: leg interosseous membranehuman foetusessexual dimorphism
References
- Bareggi R, Grill V, Zweyer M, et al. On the assessment of the growth patterns in human fetal limbs: longitudinal measurements and allometric analysis. Early Hum Dev. 1996; 45(1-2): 11–25.
- Bashamboo A, McElreavey K. Mechanism of sex determination in humans: insights from disorders of sex development. Sex Dev. 2016; 10(5-6): 313–325.
- Bogin B. Evolutionary perspective on human growth. Annu Rev Anthropol. 1999; 28: 109–153.
- Broere-Brown ZA, Baan E, Schalekamp-Timmermans S, et al. Sex-specific differences in fetal and infant growth patterns: a prospective population-based cohort study. Biol Sex Differ. 2016; 7: 65.
- Burkhart TA, Asa B, Payne MWC, et al. Anatomy of the proximal tibiofibular joint and interosseous membrane, and their contributions to joint kinematics in below-knee amputations. J Anat. 2015; 226(2): 143–149.
- Duboc V, Dufourcq P, Blader P, et al. Asymmetry of the brain: development and implications. Annu Rev Genet. 2015; 49: 647–672.
- Gawlikowska-Sroka A, Dabrowski P, Szczurowski J, et al. Influence of physiological stress on the presence of hypoplasia and fluctuating asymmetry in a medieval population from the village of Sypniewo. Int J Paleopathol. 2017; 19: 43–52.
- Gray H. Grays anatomy. Arcturus Publishing, London 2013.
- Grey S, Tanner D, van Hell JG. How right is left? Handedness modulates neural responses during morphosyntactic processing. Brain Res. 2017; 1669: 27–43.
- Hochschild J. Functional anatomy for physical therapists. 1st ed. Thieme, Stuttgart 2015.
- Iwanaga J, Gerard N, Ishak B, et al. The interosseus crural nerve: an anatomical study of a rarely described structure. Clin Anat. 2022; 35(7): 927–933.
- Karykowska A, Domagała ZA, Gworys B. Musculus peroneus longus in foetal period. Folia Morphol. 2022; 81(1): 124–133.
- Khambete P, Harlow E, Ina J, et al. Biomechanics of the distal tibiofibular syndesmosis: a systematic review of cadaveric studies. Foot Ankle Orthop. 2021; 6(2): 24730114211012701.
- Little MH, McMahon AP. Mammalian kidney development: principles, progress, and projections. Cold Spring Harb Perspect Biol. 2012; 4(5).
- Mączka G, Kulus M, Grzelak J, et al. Symmetry and Asymmetry of the Antegonial Notch. Symmetry. 2022; 14(8): 1558.
- Morley J, Fan C, McDermott K, et al. The crural interosseous membrane re-visited: a histological and microscopic study. Eur J Transl Myol. 2019; 29(3): 8340.
- Polak M. Developmental instability: causes and consequences. Oxford University Press, Oxford 2003.
- Ropper AH, Brown RH. Adams and victor’s principles of neurology 8th ed. McGraw-Hill, New York 2005.
- Siwek K, Krupa R, Mrożek A, et al. Anatomical variations of the flexor carpi ulnaris in the fetal period. Anthropol Rev. 2023; 85(4): 135–146.
- Suchanecka M, Siwek K, Ciach J, et al. Typology of flexor carpi radialis muscle in human fetuses. Folia Med Cracov. 2022; 62(1): 5–17.
- Xu D, Wang Y, Jiang C, et al. Strain distribution in the anterior inferior tibiofibular ligament, posterior inferior tibiofibular ligament, and interosseous membrane using digital image correlation. Foot Ankle Int. 2018; 39(5): 618–628.
