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Morphological and immunohistological characteristics of follicular-compact thyroid carcinoma in dog
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Abstract
The case of a 14-year-old mongrel dog with a thyroid tumor treated by thyreoidectomy is described. The resected tumor was subjected to a detailed morphological and immunohistochemical analysis utilizing antibodies directed against thyroglobulin, calcitonin, chromogranin A, cytokeratin 19, thyroid transcription factor-1, CD31, Ki-67 and minichromosome maintenance protein 3. Expression level of the above mentioned antigens allowed to characterize the resected tumor as thyroid follicular-compact carcinoma. Common application of immunohistochemistry may increase the diagnosis precision and efficacy of thyroid tumor treatment in dogs.
Abstract
The case of a 14-year-old mongrel dog with a thyroid tumor treated by thyreoidectomy is described. The resected tumor was subjected to a detailed morphological and immunohistochemical analysis utilizing antibodies directed against thyroglobulin, calcitonin, chromogranin A, cytokeratin 19, thyroid transcription factor-1, CD31, Ki-67 and minichromosome maintenance protein 3. Expression level of the above mentioned antigens allowed to characterize the resected tumor as thyroid follicular-compact carcinoma. Common application of immunohistochemistry may increase the diagnosis precision and efficacy of thyroid tumor treatment in dogs.
Keywords
thyroid cancer; follicular-compact cancer; dog
About this articleTitle
Morphological and immunohistological characteristics of follicular-compact thyroid carcinoma in dog
Journal
Folia Histochemica et Cytobiologica
Issue
Article type
Brief communication
Pages
157-161
Published online
2014-07-09
Page views
1889
Article views/downloads
2201
DOI
10.5603/FHC.2014.0009
Bibliographic record
Folia Histochem Cytobiol 2014;52(2):157-161.
Keywords
thyroid cancer
follicular-compact cancer
dog
Authors
Rafal Ciaputa
Marcin Nowak
Malgorzata Kandefer-Gola
Katarzyna Dziedzic
Pawel Halupka
Bartosz Pula
Maciej Kielbowicz
