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Vol 51, No 4 (2013)
Review paper
Submitted: 2014-02-05
Accepted: 2014-02-05
Published online: 2014-02-05
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Clinical studies monitoring circulating and disseminated tumor cells in gastrointestinal cancers

Petra Eliasova, Katarina Kolostova, Christopher Kobierzycki, Vladimir Bobek
DOI: 10.5603/FHC.2013.0037
·
Folia Histochem Cytobiol 2013;51(4):265-277.

open access

Vol 51, No 4 (2013)
REVIEW
Submitted: 2014-02-05
Accepted: 2014-02-05
Published online: 2014-02-05

Abstract

Abstract: Circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) are responsible for the development of metastatic disease, and may also hold the key to determining tailored therapies of advanced cancer disease. Our review summarizes the prognostic significance of the detection of CTCs and DTCs in various gastrointestinal cancers with an overview of their possible use as prognostic biomarkers. This could be used inthe future as a starting point for new clinical trials focusing on the predictive potential of circulating and disseminated tumor cells.

Abstract

Abstract: Circulating tumor cells (CTCs) and disseminated tumor cells (DTCs) are responsible for the development of metastatic disease, and may also hold the key to determining tailored therapies of advanced cancer disease. Our review summarizes the prognostic significance of the detection of CTCs and DTCs in various gastrointestinal cancers with an overview of their possible use as prognostic biomarkers. This could be used inthe future as a starting point for new clinical trials focusing on the predictive potential of circulating and disseminated tumor cells.

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Keywords

circulating tumor cells; gastrointestinal cancer; esophageal cancer; colorectal cancer; gastric cancer; plastin3; prognosis

About this article
Title

Clinical studies monitoring circulating and disseminated tumor cells in gastrointestinal cancers

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 51, No 4 (2013)

Article type

Review paper

Pages

265-277

Published online

2014-02-05

Page views

1650

Article views/downloads

1929

DOI

10.5603/FHC.2013.0037

Bibliographic record

Folia Histochem Cytobiol 2013;51(4):265-277.

Keywords

circulating tumor cells
gastrointestinal cancer
esophageal cancer
colorectal cancer
gastric cancer
plastin3
prognosis

Authors

Petra Eliasova
Katarina Kolostova
Christopher Kobierzycki
Vladimir Bobek

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