open access

Vol 50, No 2 (2012)
Short Communication
Published online: 2012-07-05
Submitted: 2012-01-19
Accepted: 2012-01-19
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LN-5 antibody against human macrophages cross-reacts with routinely processed human sebaceous glands

Grzegorz J. Lis, Jan A. Litwin, Alicja Furgał-Borzych, Grażyna Pyka-Fościak
DOI: 10.5603/FHC.2012.0042
·
Folia Histochem Cytobiol 2012;50(2):319-321.

open access

Vol 50, No 2 (2012)
Short Communication
Published online: 2012-07-05
Submitted: 2012-01-19
Accepted: 2012-01-19

Abstract

LN-5 monoclonal antibody against human macrophages was found to selectively stain human sebaceous glands in formalin-fixed, paraffin-embedded skin samples. Undifferentiated sebocyte progenitors were negative, and only sebocytes from the onset of their differentiation revealed positive cytoplasmic immunofluorescence. Since there are very few selective and easy-to-use markers of sebaceous glands, LN-5 antibody can offer a simple and relatively specific way to detect human sebocytes from the onset of their differentiation in routinely processed material, both freshly prepared and archival.

Abstract

LN-5 monoclonal antibody against human macrophages was found to selectively stain human sebaceous glands in formalin-fixed, paraffin-embedded skin samples. Undifferentiated sebocyte progenitors were negative, and only sebocytes from the onset of their differentiation revealed positive cytoplasmic immunofluorescence. Since there are very few selective and easy-to-use markers of sebaceous glands, LN-5 antibody can offer a simple and relatively specific way to detect human sebocytes from the onset of their differentiation in routinely processed material, both freshly prepared and archival.
Get Citation

Keywords

LN-5 antibody; sebaceous glands; human; immunofluorescence

About this article
Title

LN-5 antibody against human macrophages cross-reacts with routinely processed human sebaceous glands

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 50, No 2 (2012)

Pages

319-321

Published online

2012-07-05

DOI

10.5603/FHC.2012.0042

Bibliographic record

Folia Histochem Cytobiol 2012;50(2):319-321.

Keywords

LN-5 antibody
sebaceous glands
human
immunofluorescence

Authors

Grzegorz J. Lis
Jan A. Litwin
Alicja Furgał-Borzych
Grażyna Pyka-Fościak

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