Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm

Marta Siergiejuk; Marek Gacko; Anna Worowska

doi:10.5603/FHC.2011.0003

Vol 49, No 1 (2011)

Review paper

Submitted: 2011-12-19

Published online: 2011-04-19

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Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm

Marta Siergiejuk, Marek Gacko, Anna Worowska

DOI: 10.5603/FHC.2011.0003

Folia Histochem Cytobiol 2011;49(1):10-12.

Vol 49, No 1 (2011)

REVIEW

Submitted: 2011-12-19

Published online: 2011-04-19

Abstract

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z–Phe–Ala. It was lower on Z–Phe–Phe, Z–Glu–Tyr, Z–Glu–Phe, Z–Gly–Phe, and the lowest activity was on Z–Gly–Ala. We conclude that cathepsin A’s activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 1, pp. 10–12)

Abstract

We evaluated the cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm. We compared this activity to that of a retracted blood clot homogenate. Cathepsin A of aneurysm parietal thrombus homogenate and blood clot homogenate showed the highest activity on Z–Phe–Ala. It was lower on Z–Phe–Phe, Z–Glu–Tyr, Z–Glu–Phe, Z–Gly–Phe, and the lowest activity was on Z–Gly–Ala. We conclude that cathepsin A’s activity on a parietal thrombus of an aneurysm is much higher than blood clot cathepsin A activity. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 1, pp. 10–12)

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Keywords

parietal thrombus of abdominal aortic aneurysm; blood clots; cathepsin A

About this article

Title

Cathepsin A activity of a parietal thrombus of an abdominal aortic aneurysm

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 49, No 1 (2011)

Article type

Review paper

Pages

10-12

Published online

2011-04-19

Page views

1803

Article views/downloads

2203

DOI

10.5603/FHC.2011.0003

Bibliographic record

Folia Histochem Cytobiol 2011;49(1):10-12.

Keywords

parietal thrombus of abdominal aortic aneurysm
blood clots
cathepsin A

Authors

Marta Siergiejuk
Marek Gacko
Anna Worowska