open access

Vol 42, No 4 (2004)
Original paper
Submitted: 2011-12-19
Published online: 2005-02-12
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Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.

Grazyna Hoser, Danuta Wasilewska, Joanna Domagała-Kulawik
Folia Histochem Cytobiol 2004;42(4):249-252.

open access

Vol 42, No 4 (2004)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2005-02-12

Abstract

In recent years many data indicate that lymphocytes from cancer patients undergo increased apoptosis. The objective of this study was to evaluate the expression of Fas receptor on lymphocytes obtained from patients with lung cancer. Eighteen patients with non-small cell lung cancer and 18 healthy volunteers were investigated. Expression of Fas (CD95) on CD4+ and CD8+ blood lymphocytes was evaluated by flow cytometry. The proportion of blood Fas+ lymphocytes was significantly higher in lung cancer patients when compared with healthy individuals and in smokers when compared with nonsmokers.

Abstract

In recent years many data indicate that lymphocytes from cancer patients undergo increased apoptosis. The objective of this study was to evaluate the expression of Fas receptor on lymphocytes obtained from patients with lung cancer. Eighteen patients with non-small cell lung cancer and 18 healthy volunteers were investigated. Expression of Fas (CD95) on CD4+ and CD8+ blood lymphocytes was evaluated by flow cytometry. The proportion of blood Fas+ lymphocytes was significantly higher in lung cancer patients when compared with healthy individuals and in smokers when compared with nonsmokers.
Get Citation
About this article
Title

Expression of Fas receptor on peripheral blood lymphocytes from patients with non-small cell lung cancer.

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 42, No 4 (2004)

Article type

Original paper

Pages

249-252

Published online

2005-02-12

Bibliographic record

Folia Histochem Cytobiol 2004;42(4):249-252.

Authors

Grazyna Hoser
Danuta Wasilewska
Joanna Domagała-Kulawik

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