Vol 44, No 2 (2006)
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Published online: 2006-06-30

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NK cell depletion and recovery in SCID mice treated with anti-NK1.1 antibody.

Joanna Kulesza, Grazyna Hoser, Danuta Wasilewska, Jerzy Kawiak
Folia Histochem Cytobiol 2006;44(2):93-96.

Abstract

The anti-NK1.1 antibody produced by PK136 hybridoma cell line administered subcutaneously to SCID mice effectively decreased the level of peripheral blood NK cells and weight of the spleen for 3-4 days. The antibody treatment did not harm the general state of the animal, and may be practically applied in xenograft experiments.

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