Vol 46, No 1 (2008)
Original paper
Published online: 2008-02-26
Human cathepsin D.
DOI: 10.2478/v10042-008-0003-x
Folia Histochem Cytobiol 2008;46(1):23-38.
Abstract
A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were considered.
