Vol 46, No 1 (2008)
Original paper
Published online: 2008-02-26
Genes and structure of selected cytokines involved in pathogenesis of psoriasis.
DOI: 10.2478/v10042-008-0002-y
Folia Histochem Cytobiol 2008;46(1):11-21.
Abstract
Psoriasis is a common skin disease involving 1-4% of human population worldwide, of strong genetic background. The following cytokines are directly involved in psoriasis: TNF, IL-1, IL-2, IL-6, IL-7, IL-8, IL-15, IL-18, IL-19, IL-20, IL-23 whereas IL-4, IL-10, IL-12 as well as IL-11, IL-17 and IFN-gamma are rather indirectly engaged. This work is a review of some genetic factors and structure of selected cytokines and receptors and their genes location.
