open access

Vol 46, No 3 (2008)
Original paper
Submitted: 2011-12-19
Published online: 2008-12-06
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The evaluation of mechanical properties of animal tendons after corticosteroid therapy.

Grazyna Olchowik, Elzbieta Siek, Monika Tomaszewska, Marek Tomaszewski
DOI: 10.2478/v10042-008-0081-9
·
Folia Histochem Cytobiol 2008;46(3):373-377.

open access

Vol 46, No 3 (2008)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2008-12-06

Abstract

The purpose of the study was to examine the effect of systemic glucocorticosteroids administration on mechanical properties of animal tendons. Twenty female Wistar rats were divided into two groups and those that formed experimental group were subjected activity of hydrocortisone given to the peritoneum. Mechanical tests were performed. Hydrocortisone administration caused reduction of force value and the increase of strain, also the value of elasticity module was significantly smaller comparing to the control group. The results of biomechanical tests suggested that glucocorticoids produce less stiffness tendon, which fails in maximum point of load. This study revealed that systemic hydrocortisone administration changes significantly mechanical properties of tendons, which may cause frequent failure of the tendon.

Abstract

The purpose of the study was to examine the effect of systemic glucocorticosteroids administration on mechanical properties of animal tendons. Twenty female Wistar rats were divided into two groups and those that formed experimental group were subjected activity of hydrocortisone given to the peritoneum. Mechanical tests were performed. Hydrocortisone administration caused reduction of force value and the increase of strain, also the value of elasticity module was significantly smaller comparing to the control group. The results of biomechanical tests suggested that glucocorticoids produce less stiffness tendon, which fails in maximum point of load. This study revealed that systemic hydrocortisone administration changes significantly mechanical properties of tendons, which may cause frequent failure of the tendon.
Get Citation
About this article
Title

The evaluation of mechanical properties of animal tendons after corticosteroid therapy.

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 46, No 3 (2008)

Article type

Original paper

Pages

373-377

Published online

2008-12-06

DOI

10.2478/v10042-008-0081-9

Bibliographic record

Folia Histochem Cytobiol 2008;46(3):373-377.

Authors

Grazyna Olchowik
Elzbieta Siek
Monika Tomaszewska
Marek Tomaszewski

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