Vol 46, No 3 (2008)
Original paper
Submitted: 2011-12-19
Published online: 2008-12-06
The evaluation of mechanical properties of animal tendons after corticosteroid therapy.
Grazyna Olchowik, Elzbieta Siek, Monika Tomaszewska, Marek Tomaszewski
DOI: 10.2478/v10042-008-0081-9
·
Folia Histochem Cytobiol 2008;46(3):373-377.
Vol 46, No 3 (2008)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2008-12-06
Abstract
The purpose of the study was to examine the effect of systemic glucocorticosteroids administration on mechanical properties of animal tendons. Twenty female Wistar rats were divided into two groups and those that formed experimental group were subjected activity of hydrocortisone given to the peritoneum. Mechanical tests were performed. Hydrocortisone administration caused reduction of force value and the increase of strain, also the value of elasticity module was significantly smaller comparing to the control group. The results of biomechanical tests suggested that glucocorticoids produce less stiffness tendon, which fails in maximum point of load. This study revealed that systemic hydrocortisone administration changes significantly mechanical properties of tendons, which may cause frequent failure of the tendon.
Abstract
The purpose of the study was to examine the effect of systemic glucocorticosteroids administration on mechanical properties of animal tendons. Twenty female Wistar rats were divided into two groups and those that formed experimental group were subjected activity of hydrocortisone given to the peritoneum. Mechanical tests were performed. Hydrocortisone administration caused reduction of force value and the increase of strain, also the value of elasticity module was significantly smaller comparing to the control group. The results of biomechanical tests suggested that glucocorticoids produce less stiffness tendon, which fails in maximum point of load. This study revealed that systemic hydrocortisone administration changes significantly mechanical properties of tendons, which may cause frequent failure of the tendon.
Title
The evaluation of mechanical properties of animal tendons after corticosteroid therapy.
Journal
Folia Histochemica et Cytobiologica
Issue
Vol 46, No 3 (2008)
Article type
Original paper
Pages
373-377
Published online
2008-12-06
Page views
1974
Article views/downloads
1577
DOI
10.2478/v10042-008-0081-9
Bibliographic record
Folia Histochem Cytobiol 2008;46(3):373-377.
Authors
Grazyna Olchowik
Elzbieta Siek
Monika Tomaszewska
Marek Tomaszewski