open access

Vol 46, No 4 (2008)
Original paper
Submitted: 2011-12-19
Published online: 2009-01-15
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Effector and memory CD4+ and CD8+ T cells in the chronic infection process.

Dominika Ojdana, Kamil Safiejko, Alina Lipska, Piotr Radziwon, Jacek Dadan, Elzbieta Tryniszewska
DOI: 10.2478/v10042-008-0077-5
·
Folia Histochem Cytobiol 2008;46(4):413-417.

open access

Vol 46, No 4 (2008)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2009-01-15

Abstract

T cell memory in comparison with B cell memory is not well understood. This review focuses on CD8+ and CD4+ memory T cells. In this article we try to define memory cells and also present models of memory T cells formation. We would also like to delineate their differentiation into distinct subsets. Long-lived memory T cells consist in two main subsets: TCM and TEM. Recent studies have shown that not all cells considered to be memory cells differentiate into TCM and TEM, but a small proportion of theses cells exhibit naive cells phenotype. Memory T cells constitute a heterogeneous population of cells. In this study we lay stress on characteristic of main memory T cells subsets and their alleged participation in immune response upon reexposure to the Ag.

Abstract

T cell memory in comparison with B cell memory is not well understood. This review focuses on CD8+ and CD4+ memory T cells. In this article we try to define memory cells and also present models of memory T cells formation. We would also like to delineate their differentiation into distinct subsets. Long-lived memory T cells consist in two main subsets: TCM and TEM. Recent studies have shown that not all cells considered to be memory cells differentiate into TCM and TEM, but a small proportion of theses cells exhibit naive cells phenotype. Memory T cells constitute a heterogeneous population of cells. In this study we lay stress on characteristic of main memory T cells subsets and their alleged participation in immune response upon reexposure to the Ag.
Get Citation
About this article
Title

Effector and memory CD4+ and CD8+ T cells in the chronic infection process.

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 46, No 4 (2008)

Article type

Original paper

Pages

413-417

Published online

2009-01-15

DOI

10.2478/v10042-008-0077-5

Bibliographic record

Folia Histochem Cytobiol 2008;46(4):413-417.

Authors

Dominika Ojdana
Kamil Safiejko
Alina Lipska
Piotr Radziwon
Jacek Dadan
Elzbieta Tryniszewska

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