The inflammatory reaction during chronic venous disease of lower limbs.

Dominika Ojdana; Kamil Safiejko; Alina Lipska; Paweł Sacha; Piotr Wieczorek; Piotr Radziwon; Jacek Dadan; Elzbieta Tryniszewska

doi:10.2478/v10042-009-0029-8

Vol 47, No 2 (2009)

Original paper

Submitted: 2011-12-19

Published online: 2009-12-10

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The inflammatory reaction during chronic venous disease of lower limbs.

Dominika Ojdana, Kamil Safiejko, Alina Lipska, Paweł Sacha, Piotr Wieczorek, Piotr Radziwon, Jacek Dadan, Elzbieta Tryniszewska

DOI: 10.2478/v10042-009-0029-8

Folia Histochem Cytobiol 2009;47(2):185-189.

Vol 47, No 2 (2009)

ORIGINAL PAPERS

Submitted: 2011-12-19

Published online: 2009-12-10

Abstract

Chronic venous disease (CVD) is an insufficiency of distal veins caused by their partial or total obstruction, endothelial distension and functional disorders. Chronic venous disease of lower limbs is common problem and affects millions of people. In this article we suggest that inflammatory process is involved in the structural remodeling in venous valves and in the venous wall, leading to valvular incompetence and the development of varicose veins.