open access

Vol 47, No 3 (2009)
ORIGINAL PAPERS
Published online: 2010-02-19
Submitted: 2011-12-19
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The aromatase expression in myomas and myometriums of women in reproduction and perimenopausal age.

Paweł Madej, Andrzej Plewka, Danuta Plewka, Piotr Paleń, Grazyna Nowaczyk, Edyta Bogunia, Jacek Marczyński, Józef Waloszek
DOI: 10.2478/v10042-009-0105-0
·
Folia Histochem Cytobiol 2009;47(3):497-504.

open access

Vol 47, No 3 (2009)
ORIGINAL PAPERS
Published online: 2010-02-19
Submitted: 2011-12-19

Abstract

Uterine myomas represent one of the most common female pathologies. Uterine smooth muscle myomas or fibromas are benign tumours which respond to hormones and their etiology induces wide interest. The myomas were found to contain aromatase and, in addition, cells of the myomas were found to synthesize estrogen. This study was conducted on patients with the myomas, in either generative age or in the perimenopausal period. Expression of aromatase was detected in patients of various age, with large or small uterine myomas, using an immunohistochemical technique. In addition expression of the enzyme was examined at the periphery of every myoma.

Abstract

Uterine myomas represent one of the most common female pathologies. Uterine smooth muscle myomas or fibromas are benign tumours which respond to hormones and their etiology induces wide interest. The myomas were found to contain aromatase and, in addition, cells of the myomas were found to synthesize estrogen. This study was conducted on patients with the myomas, in either generative age or in the perimenopausal period. Expression of aromatase was detected in patients of various age, with large or small uterine myomas, using an immunohistochemical technique. In addition expression of the enzyme was examined at the periphery of every myoma.
Get Citation
About this article
Title

The aromatase expression in myomas and myometriums of women in reproduction and perimenopausal age.

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 47, No 3 (2009)

Pages

497-504

Published online

2010-02-19

DOI

10.2478/v10042-009-0105-0

Bibliographic record

Folia Histochem Cytobiol 2009;47(3):497-504.

Authors

Paweł Madej
Andrzej Plewka
Danuta Plewka
Piotr Paleń
Grazyna Nowaczyk
Edyta Bogunia
Jacek Marczyński
Józef Waloszek

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