open access
Vol 48, No 2 (2010)
Original paper
Submitted: 2011-12-19
Published online: 2010-08-03
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Antifungal activity of triterpenoid isolated from Azima tetracantha leaves.
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DOI: 10.2478/v10042-010-0005-3
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Folia Histochem Cytobiol 2010;48(2):311-313.
open access
Vol 48, No 2 (2010)
ORIGINAL PAPERS
Submitted: 2011-12-19
Published online: 2010-08-03
Abstract
The present study was designed to evaluate the antifungal activity of Azima tetracantha extracts and isolated compound (friedelin) against fungi. Antifungal activity was carried out using broth microdilution method and fractions were collected using (silica gel) column chromatography. The antifungal activity of Azima tetracantha crude extracts and isolated compound (friedelin) were evaluated using the micro dilution method. Hexane extract showed some antifungal activity. The compound also exhibited antifungal activity against tested fungi. The lowest MIC against Trichophyton rubrum (296) was 62.5 microg/ml and the MIC for Curvularia lunata was 62.5 microg/ml. These results suggest that Friedelin is a promising antifungal agent.
Abstract
The present study was designed to evaluate the antifungal activity of Azima tetracantha extracts and isolated compound (friedelin) against fungi. Antifungal activity was carried out using broth microdilution method and fractions were collected using (silica gel) column chromatography. The antifungal activity of Azima tetracantha crude extracts and isolated compound (friedelin) were evaluated using the micro dilution method. Hexane extract showed some antifungal activity. The compound also exhibited antifungal activity against tested fungi. The lowest MIC against Trichophyton rubrum (296) was 62.5 microg/ml and the MIC for Curvularia lunata was 62.5 microg/ml. These results suggest that Friedelin is a promising antifungal agent.
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About this articleTitle
Antifungal activity of triterpenoid isolated from Azima tetracantha leaves.
Journal
Folia Histochemica et Cytobiologica
Issue
Article type
Original paper
Pages
311-313
Published online
2010-08-03
Page views
2360
Article views/downloads
2319
DOI
10.2478/v10042-010-0005-3
Bibliographic record
Folia Histochem Cytobiol 2010;48(2):311-313.
Authors
V Duraipandiyan
M Gnanasekar
S Ignacimuthu
