open access

Vol 48, No 2 (2010)
Original paper
Published online: 2010-08-03
Submitted: 2011-12-19
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Antifungal activity of triterpenoid isolated from Azima tetracantha leaves.

V Duraipandiyan, M Gnanasekar, S Ignacimuthu
DOI: 10.2478/v10042-010-0005-3
·
Folia Histochem Cytobiol 2010;48(2):311-313.

open access

Vol 48, No 2 (2010)
ORIGINAL PAPERS
Published online: 2010-08-03
Submitted: 2011-12-19

Abstract

The present study was designed to evaluate the antifungal activity of Azima tetracantha extracts and isolated compound (friedelin) against fungi. Antifungal activity was carried out using broth microdilution method and fractions were collected using (silica gel) column chromatography. The antifungal activity of Azima tetracantha crude extracts and isolated compound (friedelin) were evaluated using the micro dilution method. Hexane extract showed some antifungal activity. The compound also exhibited antifungal activity against tested fungi. The lowest MIC against Trichophyton rubrum (296) was 62.5 microg/ml and the MIC for Curvularia lunata was 62.5 microg/ml. These results suggest that Friedelin is a promising antifungal agent.

Abstract

The present study was designed to evaluate the antifungal activity of Azima tetracantha extracts and isolated compound (friedelin) against fungi. Antifungal activity was carried out using broth microdilution method and fractions were collected using (silica gel) column chromatography. The antifungal activity of Azima tetracantha crude extracts and isolated compound (friedelin) were evaluated using the micro dilution method. Hexane extract showed some antifungal activity. The compound also exhibited antifungal activity against tested fungi. The lowest MIC against Trichophyton rubrum (296) was 62.5 microg/ml and the MIC for Curvularia lunata was 62.5 microg/ml. These results suggest that Friedelin is a promising antifungal agent.
Get Citation
About this article
Title

Antifungal activity of triterpenoid isolated from Azima tetracantha leaves.

Journal

Folia Histochemica et Cytobiologica

Issue

Vol 48, No 2 (2010)

Article type

Original paper

Pages

311-313

Published online

2010-08-03

DOI

10.2478/v10042-010-0005-3

Bibliographic record

Folia Histochem Cytobiol 2010;48(2):311-313.

Authors

V Duraipandiyan
M Gnanasekar
S Ignacimuthu

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