Vol 50, No 2 (2012)
Brief communication
Published online: 2012-07-05
LN-5 antibody against human macrophages cross-reacts with routinely processed human sebaceous glands
DOI: 10.5603/FHC.2012.0042
Folia Histochem Cytobiol 2012;50(2):319-321.
Abstract
LN-5 monoclonal antibody against human macrophages was found to selectively stain human sebaceous glands in formalin-fixed, paraffin-embedded skin samples. Undifferentiated sebocyte progenitors were negative, and only sebocytes from the onset of their differentiation revealed positive cytoplasmic immunofluorescence. Since there are very few selective and easy-to-use markers of sebaceous glands, LN-5 antibody can offer a simple and relatively specific way to detect human sebocytes from the onset of their differentiation in routinely processed material, both freshly prepared and archival.
Keywords: LN-5 antibodysebaceous glandshumanimmunofluorescence
![](https://journals.viamedica.pl/plugins/generic/popups/images/icons/close.png)