open access

Vol 13, No 4 (2018)
Original Papers
Published online: 2018-09-12
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Analgesic drug use in patients with coronary artery disease

Agnieszka Olszanecka, Łukasz Reczek, Martyna Schönborn, Sebastian Janiec, Małgorzata Cebeńko, Izabela Pałasz, Danuta Czarnecka
DOI: 10.5603/FC.2018.0065
·
Folia Cardiologica 2018;13(4):283-288.

open access

Vol 13, No 4 (2018)
Original Papers
Published online: 2018-09-12

Abstract

Introduction. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the management of pain in a variety of conditions. Available data clearly indicate, that the use of NSAIDs is associated with a number of adverse effects, especially in patients with cardiovascular disease. The aim of the study was to assess the prevalence and frequency of analgesic drug use in patients with coronary heart disease and knowledge about possible interactions of these drugs with conventional cardiac therapy.

Material and methods. The study included 183 patients with ischaemic heart disease, hospitalised in the tertiary cardiological centre. Data on the use of analgesics and patients’ knowledge about their safety were collected using self-prepared questionnaire. Information about current medication, accompanying diseases and blood-test results were checked in patients’ medical records.

Results. In the examined group, regular use of analgesic drugs (defined as at least three times per week) was reported by 29 subjects  (15.8%). The most frequently used analgesics were NSAIDs and paracetamol, with their regular use reported by 7.0% and 8.8% of the respondents respectively. The majority of patients using NSAIDs were not aware about their possible interactions with antiplatelet therapy and did not consult the use of analgesics with a physician. Only 19.8% of patients admitted, that they received the information about analgesics from their doctor.

Conclusions. The regular use of analgesic drugs by 15.8% of patients with coronary artery disease is a significant concern. Patients with coronary heart disease should be provided with detailed information and recommendations about safe analgesic therapy and alternatives for NSAIDs.

Abstract

Introduction. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the management of pain in a variety of conditions. Available data clearly indicate, that the use of NSAIDs is associated with a number of adverse effects, especially in patients with cardiovascular disease. The aim of the study was to assess the prevalence and frequency of analgesic drug use in patients with coronary heart disease and knowledge about possible interactions of these drugs with conventional cardiac therapy.

Material and methods. The study included 183 patients with ischaemic heart disease, hospitalised in the tertiary cardiological centre. Data on the use of analgesics and patients’ knowledge about their safety were collected using self-prepared questionnaire. Information about current medication, accompanying diseases and blood-test results were checked in patients’ medical records.

Results. In the examined group, regular use of analgesic drugs (defined as at least three times per week) was reported by 29 subjects  (15.8%). The most frequently used analgesics were NSAIDs and paracetamol, with their regular use reported by 7.0% and 8.8% of the respondents respectively. The majority of patients using NSAIDs were not aware about their possible interactions with antiplatelet therapy and did not consult the use of analgesics with a physician. Only 19.8% of patients admitted, that they received the information about analgesics from their doctor.

Conclusions. The regular use of analgesic drugs by 15.8% of patients with coronary artery disease is a significant concern. Patients with coronary heart disease should be provided with detailed information and recommendations about safe analgesic therapy and alternatives for NSAIDs.

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Keywords

coronary artery disease, analgesics, NSAIDs, cardiovascular risk

About this article
Title

Analgesic drug use in patients with coronary artery disease

Journal

Folia Cardiologica

Issue

Vol 13, No 4 (2018)

Pages

283-288

Published online

2018-09-12

DOI

10.5603/FC.2018.0065

Bibliographic record

Folia Cardiologica 2018;13(4):283-288.

Keywords

coronary artery disease
analgesics
NSAIDs
cardiovascular risk

Authors

Agnieszka Olszanecka
Łukasz Reczek
Martyna Schönborn
Sebastian Janiec
Małgorzata Cebeńko
Izabela Pałasz
Danuta Czarnecka

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