open access

Vol 10, No 5 (2015)
Review Papers
Published online: 2015-10-28
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Muscle symptoms on statins — facts, myths, reality, and expert statements

Katarzyna Starzyk, Beata Wożakowska-Kapłon
DOI: 10.5603/FC.2015.0059
·
Folia Cardiologica 2015;10(5):354-360.

open access

Vol 10, No 5 (2015)
Review Papers
Published online: 2015-10-28

Abstract

Statin therapy is a fundamental treatment for hypercholesterolaemia. Statin-associated muscle symptoms (SAMS) are one of the main reasons for treatment discontinuation and failure to reduce the risk for cardiovascular events. Strategy for optimal management of patients with SAMS should include the use of a statin that is best tolerated by the patient, dosing the drug even more rarely than once daily, or introducing a combination therapy with other drug known to significantly decrease LDL cholesterol and have a proven effect on cardiovascular risk reduction. Proper diagnosis of muscle symptoms, associated or not associated with statin therapy, and introducing adequate management allows achieving benefits resulting from decreased cholesterol level avoiding adverse effects and, subsequently, provides cardiovascular risk reduction.

Abstract

Statin therapy is a fundamental treatment for hypercholesterolaemia. Statin-associated muscle symptoms (SAMS) are one of the main reasons for treatment discontinuation and failure to reduce the risk for cardiovascular events. Strategy for optimal management of patients with SAMS should include the use of a statin that is best tolerated by the patient, dosing the drug even more rarely than once daily, or introducing a combination therapy with other drug known to significantly decrease LDL cholesterol and have a proven effect on cardiovascular risk reduction. Proper diagnosis of muscle symptoms, associated or not associated with statin therapy, and introducing adequate management allows achieving benefits resulting from decreased cholesterol level avoiding adverse effects and, subsequently, provides cardiovascular risk reduction.

Get Citation

Keywords

statins, hypercholesterolaemia, muscular symptoms

About this article
Title

Muscle symptoms on statins — facts, myths, reality, and expert statements

Journal

Folia Cardiologica

Issue

Vol 10, No 5 (2015)

Pages

354-360

Published online

2015-10-28

DOI

10.5603/FC.2015.0059

Bibliographic record

Folia Cardiologica 2015;10(5):354-360.

Keywords

statins
hypercholesterolaemia
muscular symptoms

Authors

Katarzyna Starzyk
Beata Wożakowska-Kapłon

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