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Vol 10, No 1 (2015)
Review paper
Published online: 2015-03-02

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New directions in research on non-vitamin K antagonist oral anticoagulants at the beginning of 2015 — the results of which clinical trials are waiting for?

Mariusz Tomaniak, Aleksandra Gąsecka, Krzysztof J. Filipiak
Folia Cardiologica 2015;10(1):25-37.

Abstract

Non-vitamin K antagonist oral anticoagulants (NOAC) are no longer a new topic in clinical practice. Meta-analyzes summarizing clinical studies on NOAC’ safety and efficacy indicate that these drugs constitute a very promising therapeutic group. As a consequence, they will play an increasingly important role in clinical practice. Ongoing multicenter studies are likely to allow for further expansion of clinical indications for their use and overcome current obstacles associated with their use. The following article summarizes the most important directions in research on NOAC.

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