open access

Vol 10, No 1 (2015)
Guidelines and Clinical Practice — a Discussion Forum for Cardiologists
Published online: 2015-03-02
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Proarrhythmic effect of propafenone — a case report

Konrad Jarząbek, Maciej Młodnicki, Elżbieta Jaskulska-Niedziela, Dawid Bąkowski, Beata Wożakowska-Kapłon
DOI: 10.5603/FC.2015.0009
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Folia Cardiologica 2015;10(1):55-57.

open access

Vol 10, No 1 (2015)
Guidelines and Clinical Practice — a Discussion Forum for Cardiologists
Published online: 2015-03-02

Abstract

Propafenone is used in the therapy of supraventricular arrhythmias. Its long-term use may be associated with the development of malignant ventricular arrhythmias. We present a case of a patient with paroxysmal atrial fibrillation, who was administered an oral dose of 600 mg of propafenone, which resulted in an episode of ventricular tachycardia. This article indicates that patients without severe heart failure subjected to therapeutic doses of propafenone are also exposed to the possibility of its adverse effects.

Abstract

Propafenone is used in the therapy of supraventricular arrhythmias. Its long-term use may be associated with the development of malignant ventricular arrhythmias. We present a case of a patient with paroxysmal atrial fibrillation, who was administered an oral dose of 600 mg of propafenone, which resulted in an episode of ventricular tachycardia. This article indicates that patients without severe heart failure subjected to therapeutic doses of propafenone are also exposed to the possibility of its adverse effects.

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Keywords

propafenone, atrial fibrillation, ventricular tachycardia

About this article
Title

Proarrhythmic effect of propafenone — a case report

Journal

Folia Cardiologica

Issue

Vol 10, No 1 (2015)

Pages

55-57

Published online

2015-03-02

DOI

10.5603/FC.2015.0009

Bibliographic record

Folia Cardiologica 2015;10(1):55-57.

Keywords

propafenone
atrial fibrillation
ventricular tachycardia

Authors

Konrad Jarząbek
Maciej Młodnicki
Elżbieta Jaskulska-Niedziela
Dawid Bąkowski
Beata Wożakowska-Kapłon

References (9)
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  4. Wiesfeld ACP, Ansink JM, van Veldhuisen DJ, et al. Broad complex tachycardia during treatment of atrial fibrillation with a 1c antiarrhythmic drug: ventricular or supraventricular proarrhythmia? Int J Cardiol. 2006; 107(1): 140–141.
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  7. Wożakowska-Kapłon B, Stępień-Wałek A. Przedwakowanie propafenonu: nagłe zatrzymanie krążenia i całkowity powrót do zdrowia. Folia Cardiol Excerpta. 2011; 6: 72–75.
  8. el-Harari MB, Adams PC. Atrial flutter with 1:1 atrioventricular conduction caused by propafenone. Pacing Clin Electrophysiol. 1998; 21(10): 1999–2001.
  9. Crijns HJ, van Gelder IC, Lie KI. Supraventricular tachycardia mimicking ventricular tachycardia during flecainide treatment. Am J Cardiol. 1988; 62(17): 1303–1306.

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