Tom 10, Nr 1 (2015)
Artykuł przeglądowy
Opublikowany online: 2015-03-02
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Łagodna hipotermia terapeutyczna po nagłym zatrzymaniu krążenia w przebiegu ostrego zespołu wieńcowego – doświadczenia z wdrażania metody.
DOI: 10.5603/FC.2015.0005
Folia Cardiologica 2015;10(1):19-24.
Streszczenie
Wysoką śmiertelność wśród pacjentów, u których osiągnięto powrót spontanicznego krążenia po jego zatrzymaniu, można przypisać różnym procesom patofizjologicznym. Działająca wielokierunkowo łagodna hipotermia terapeutyczna (MTH) jest — jak dotąd — jedyną terapią, w odniesieniu do której udowodniono, że zwiększa przeżywalność pacjentów po zatrzymaniu krążenia. Europejskie Towarzystwo Kardiologiczne w 2012 roku przyznało hipotermii terapeutycznej stosowanej po nagłym zatrzymaniu krążenia najwyższą klasę wskazań I/B. Hipotermia, ze względu na swój skomplikowany mechanizm, wywiera zarówno pożądane, jak i niepożądane działania na organizm. Sposób jej stosowania i monitorowania są nadal kwestią sporną. Celem niniejszej pracy było podsumowanie obecnej wiedzy na temat stosowania MTH po nagłym zatrzymaniu krążenia.
Słowa kluczowe: hipotermia terapeutycznazatrzymanie krążeniałagodna hipotermia
Referencje
- Hossmann KA, Oschlies U, Schwindt W, et al. Electron microscopic investigation of rat brain after brief cardiac arrest. Acta Neuropathol. 2001; 101(2): 101–113.
- Neumar RW, Nolan JP, Adrie C, et al. Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council. Circulation. 2008; 118(23): 2452–2483.
- Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest. N Engl J Med. 2002; 346(8): 549–556.
- Steg PhG, James SK, Atar D, et al. Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012; 33(20): 2569–2619.
- Nolan JP, Handley AJ, Koster R, et al. European Council Guidelines for 2010. Resuscitation. 2010; 67: S3–S189.
- Polderman KH. Mechanisms of action, physiological effects, and complications of hypothermia. Crit Care Med. 2009; 37(7 Suppl): S186–S202.
- Bernard SA, Smith K, Cameron P, et al. Rapid Infusion of Cold Hartmanns Investigators. Induction of prehospital therapeutic hypothermia after resuscitation from nonventricular fibrillation cardiac arrest*. Crit Care Med. 2012; 40(3): 747–753.
- Bernard SA, Smith K, Cameron P, et al. Rapid Infusion of Cold Hartmanns (RICH) Investigators. Induction of therapeutic hypothermia by paramedics after resuscitation from out-of-hospital ventricular fibrillation cardiac arrest: a randomized controlled trial. Circulation. 2010; 122(7): 737–742.
- Bernard SA, Gray TW, Buist MD, et al. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002; 346(8): 557–563.
- Lopez-de-Sa E, Rey JR, Armada E, et al. Hypothermia in comatose survivors from out-of-hospital cardiac arrest: pilot trial comparing 2 levels of target temperature. Circulation. 2012; 126(24): 2826–2833.
- Chandrasekaran PN, Dezfulian C, Polderman KH, et al. TTM Trial Investigators. Targeted temperature management at 33°C versus 36°C after cardiac arrest. N Engl J Med. 2013; 369(23): 2197–2206.
- Varon J, Acosta P. Therapeutic hypothermia: past, present, and future. Chest. 2008; 133(5): 1267–1274.
- Al-Senani FM, Graffagnino C, Grotta JC, et al. A prospective, multicenter pilot study to evaluate the feasibility and safety of using the CoolGard System and Icy catheter following cardiac arrest. Resuscitation. 2004; 62(2): 143–150.
- Taccone FS, Donadello K, Beumier M, et al. When, where and how to initiate hypothermia after adult cardiac arrest. Minerva Anestesiol. 2011; 77(9): 927–933.
- Broessner G, Fischer M, Schubert G, et al. Update on therapeutic temperature management. Crit Care. 2012; 16(supl. 2): A1.
- Mayer SA, Kowalski RG, Presciutti M, et al. Clinical trial of a novel surface cooling system for fever control in neurocritical care patients. Crit Care Med. 2004; 32(12): 2508–2515.
- Harris BA, Andrews PJD, Marshall I, et al. Forced convective head cooling device reduces human cross-sectional brain temperature measured by magnetic resonance: a non-randomized healthy volunteer pilot study. Br J Anaesth. 2008; 100(3): 365–372.
- Busch H, Fritz H, Eichwede F, et al. Intra-arrest cooling using a novel intra-nasal cooling method for immediate induction of therapeutic hypothermia in Germany. Critical Care. 2010; 14(Suppl 1): P320.
- Sterz F, Holzer M, Roine R, et al. Hypothermia after cardiac arrest: a treatment that works. Curr Opin Crit Care. 2003; 9(3): 205–210.
- Kämäräinen A, Virkkunen I, Tenhunen J, et al. Induction of therapeutic hypothermia after cardiac arrest in prehospital patients using ice-cold Ringer's solution: a pilot study. Resuscitation. 2004; 62(3): 299–302.
- Kliegel A, Losert H, Sterz F, et al. Cold simple intravenous infusions preceding special endovascular cooling for faster induction of mild hypothermia after cardiac arrest--a feasibility study. Resuscitation. 2005; 64(3): 347–351.
- Bernard S, Buist M, Monteiro O, et al. Induced hypothermia using large volume, ice-cold intravenous fluid in comatose survivors of out-of-hospital cardiac arrest: a preliminary report. Resuscitation. 2003; 56(1): 9–13.
- Safar P, Kochanek P. Therapeutic Hypothermia after Cardiac Arrest. New England Journal of Medicine. 2002; 346(8): 612–613.
- Sunde K. Therapeutic hypothermia with endovascular cooling. Scand J Trauma Resusc Emerg Med. 2004; 12: 23–25.
- Zeiner A, Holzer M, Sterz F, et al. Mild resuscitative hypothermia to improve neurological outcome after cardiac arrest. A clinical feasibility trial. Hypothermia After Cardiac Arrest (HACA) Study Group. Stroke. 2000; 31(1): 86–94.
- Alzaga AG, Cerdan M, Varon J. Therapeutic hypothermia. Resuscitation. 2006; 70(3): 369–380.
- Tisherman S. Hypothermia and injury. Current Opinion in Critical Care. 2004; 10(4): 512–519.
- Donnino MW, Andersen LW, Berg KM, et al. ILCOR ALS Task Force, ILCOR ALS Task Force, Advancement Life support Task Force of the International Liaison committee on Resuscitation, International Liaison Committee on Resuscitation. Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation. Circulation. 2003; 108(1): 118–121.
- Wojewódzka-Żelezniakowicz M, Czaban SL, Szczesiul P, et al. Hipotermia poresuscytacyjna — wskazania, sposób prowadzenia, skuteczność kliniczna, powikłania stosowania. Post. Nauk Med. 2009; 11: 901–906.
- Camboni D, Philipp A, Schebesch KM, et al. Accuracy of core temperature measurement in deep hypothermic circulatory arrest. Interact Cardiovasc Thorac Surg. 2008; 7(5): 922–924.
- Polderman KH, Herold I. Therapeutic hypothermia and controlled normothermia in the intensive care unit: practical considerations, side effects, and cooling methods. Crit Care Med. 2009; 37(3): 1101–1120.
- Polderman KH. Application of therapeutic hypothermia in the intensive care unit. Opportunities and pitfalls of a promising treatment modality--Part 2: Practical aspects and side effects. Intensive Care Med. 2004; 30(5): 757–769.
- Maxwell WL, Watson A, Queen R, et al. Slow, medium, or fast re-warming following post-traumatic hypothermia therapy? An ultrastructural perspective. J Neurotrauma. 2005; 22(8): 873–884.
- Kawahara F, Kadoi Y, Saito S, et al. Slow rewarming improves jugular venous oxygen saturation during rewarming. Acta Anaesthesiol Scand. 2003; 47(4): 419–424.
- Polderman KH. Induced hypothermia and fever control for prevention and treatment of neurological injuries. Lancet. 2008; 371(9628): 1955–1969.
- Dae MW, Gao DW, Sessler DI, et al. Effect of endovascular cooling on myocardial temperature, infarct size, and cardiac output in human-sized pigs. Am J Physiol Heart Circ Physiol. 2002; 282(5): H1584–H1591.
- Bernard SA, Gray TW, Buist MD, et al. Clinical trial of induced hypothermia in comatose survivors of out-of-hospital cardiac arrest. Ann Emerg Med. 1997; 30(2): 146–153.
- Nielsen N, Sunde K, Hovdenes J, et al. Hypothermia Network. Adverse events and their relation to mortality in out-of-hospital cardiac arrest patients treated with therapeutic hypothermia. Crit Care Med. 2011; 39(1): 57–64.
- Kamps M, Bisschops LA, van der Hoeven JG, et al. Hypothermia does not increase the risk of infection: a case control study. Crit Care. 2011; 15(1): R48.
- Valeri CR, Feingold H, Cassidy G, et al. Hypothermia-induced reversible platelet dysfunction. Ann Surg. 1987; 205(2): 175–181.
- Wolberg AS, Meng ZH, Monroe DM, et al. A systematic evaluation of the effect of temperature on coagulation enzyme activity and platelet function. J Trauma. 2004; 56(6): 1221–1228.
- Spiel AO, Frossard M, Mayr FB, et al. Pronounced platelet hyperfunction in patients with cardiac arrest achieving restoration of spontaneous circulation. Crit Care Med. 2009; 37(3): 975–979.
- Schneider A, Böttiger BW, Popp E. Cerebral resuscitation after cardiocirculatory arrest. Anesth Analg. 2009; 108(3): 971–979.
- Tortorici MA, Kochanek PM, Poloyac SM. Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia-mediated alterations on the cytochrome P450 enzyme system. Crit Care Med. 2007; 35(9): 2196–2204.
- Leslie K, Sessler DI, Bjorksten AR, et al. Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium. Anesth Analg. 1995; 80(5): 1007–1014.
- Caldwell JE, Heier T, Wright PM, et al. Temperature-dependent pharmacokinetics and pharmacodynamics of vecuronium. Anesthesiology. 2000; 92(1): 84–93.
- Ibrahim K, Christoph M, Schmeinck S, et al. High rates of prasugrel and ticagrelor non-responder in patients treated with therapeutic hypothermia after cardiac arrest. Resuscitation. 2014; 85(5): 649–656.
- Joffre J, Varenne O, Bougouin W, et al. Stent thrombosis: an increased adverse event after angioplasty following resuscitated cardiac arrest. Resuscitation. 2014; 85(6): 769–773.
- Kozinski M, Pstragowski K, Kubica JM, et al. ACS network-based implementation of therapeutic hypothermia for the treatment of comatose out-of-hospital cardiac arrest survivors improves clinical outcomes: the first European experience. Scand J Trauma Resusc Emerg Med. 2013; 21: 22.
- Dumas F, White L, Stubbs BA, et al. Long-term prognosis following resuscitation from out of hospital cardiac arrest: role of percutaneous coronary intervention and therapeutic hypothermia. J Am Coll Cardiol. 2012; 60(1): 21–27.
