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Life-threatening hypophosphataemia secondary to zoledronic acid implementation in a middle-age patient who presented with advanced osteolysis in the course of multiple myeloma
Affiliations- Department of Internal Diseases and Endocrinology, Public Central Teaching Hospital, Medical University of Warsaw, Poland, Poland
- 2nd Department of Clinical Radiology, University Clinical Centre, Medical University of Warsaw, Warsaw, Poland
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Abstract
Not required for Clinical Vignette.
Abstract
Not required for Clinical Vignette.
Keywords
hypophosphatemia; zoledronic acid; osteolysis; multiple myeloma
About this articleTitle
Life-threatening hypophosphataemia secondary to zoledronic acid implementation in a middle-age patient who presented with advanced osteolysis in the course of multiple myeloma
Journal
Issue
Article type
Clinical vignette
Pages
100-101
Published online
2019-10-23
Page views
1600
Article views/downloads
708
DOI
10.5603/EP.a2019.0048
Pubmed
Bibliographic record
Endokrynol Pol 2020;71(1):100-101.
Keywords
hypophosphatemia
zoledronic acid
osteolysis
multiple myeloma
Authors
Mikołaj Radziszewski
Anna Karpiłowska
Joanna Podgórska
Anna Ziółkowska
Michał Popow
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- Harmer D, Falank C, Reagan MR. Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma. Front Endocrinol (Lausanne). 2018; 9: 788.
- Russell RG, Watts NB, Ebetino FH, et al. Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. Osteoporos Int. 2008; 19: 733–759.
- Chiam P, Manju C, Chiam P, et al. Profound and protracted hypophosphatemia after a single dose of zoledronic acid infusion for osteoporosis associated with normocalcemic primary hyperparathyroidism. Med Case Rep. 2017; 3: 1–4.
- Torimoto K, Okada Y, Arao T, et al. A case of zoledronate-induced tubulointerstitial nephritis with Fanconi syndrome. Endocr J. 2012; 59(12): 1051–1056.
- Payne RB. Renal tubular reabsorption of phosphate (TmP/GFR): indications and interpretation. Ann Clin Biochem. 1998; 35 ( Pt 2): 201–206.
