open access
Neuroendocrine tumour metastasis to the orbit


- Medical University of Gdańsk, Gdańsk, Poland
open access
Abstract
Neuroendocrine neoplasms are tumours that usually arise in the gastrointestinal tract and the bronchopulmonary system. The orbit is a rare anatomical site for their metastases. In the following article we present a case report of a 73-year-old man who was admitted to the Ophthalmology Department because of eye pain and high intraocular pressure in the right eye. There was also eye motility restriction, diplopia, oedema of the eyelid, and subconjunctival haemorrhage. Magnetic resonance imaging revealed a tumour in the right orbit, probably arising from the inferior rectus muscle. The patient was qualified for surgery, during which orbit decompression was conducted and a sample of the tumour tissue was collected. Based on the biopsy of the lesion, diagnosis of a metastatic neuroendocrine neoplasm, probably of gastrointestinal origin, was made. Further diagnostic procedures revealed metastases to other organs, and the patient was qualified for oncological treatment. In this case, orbital metastasis was the first diagnosed location of the neoplasm.
Abstract
Neuroendocrine neoplasms are tumours that usually arise in the gastrointestinal tract and the bronchopulmonary system. The orbit is a rare anatomical site for their metastases. In the following article we present a case report of a 73-year-old man who was admitted to the Ophthalmology Department because of eye pain and high intraocular pressure in the right eye. There was also eye motility restriction, diplopia, oedema of the eyelid, and subconjunctival haemorrhage. Magnetic resonance imaging revealed a tumour in the right orbit, probably arising from the inferior rectus muscle. The patient was qualified for surgery, during which orbit decompression was conducted and a sample of the tumour tissue was collected. Based on the biopsy of the lesion, diagnosis of a metastatic neuroendocrine neoplasm, probably of gastrointestinal origin, was made. Further diagnostic procedures revealed metastases to other organs, and the patient was qualified for oncological treatment. In this case, orbital metastasis was the first diagnosed location of the neoplasm.
Keywords
neuroendocrine neoplasm; carcinoma; orbit; extraocular muscles; metastasis; intraocular pressure


Title
Neuroendocrine tumour metastasis to the orbit
Journal
Issue
Article type
Clinical vignette
Pages
455-456
Published online
2019-05-27
Page views
1272
Article views/downloads
631
DOI
10.5603/EP.a2019.0024
Pubmed
Bibliographic record
Endokrynol Pol 2019;70(5):455-456.
Keywords
neuroendocrine neoplasm
carcinoma
orbit
extraocular muscles
metastasis
intraocular pressure
Authors
Karolina Kozubowska
Andrzej Skorek
Rafał Pęksa