open access

Vol 67, No 2 (2016)
Original papers
Published online: 2016-01-21
Submitted: 2015-08-07
Accepted: 2015-10-06
Get Citation

Differentiation of thyroid nodules in multinodular goiter with the application of technical ultrasound advances — initial results

Bartosz Migda, Rafal Słapa, Jacek Bierca, Jadwiga Slowińska-Srzednicka, Anna Migda, Katarzyna Dobruch-Sobczak, Wiesław Jakubowski
DOI: 10.5603/EP.a2016.0026
·
Endokrynologia Polska 2016;67(2):157-165.

open access

Vol 67, No 2 (2016)
Original papers
Published online: 2016-01-21
Submitted: 2015-08-07
Accepted: 2015-10-06

Abstract

Introduction: To evaluate the relative value of technical ultrasound advances in differentiation of thyroid nodules in multinodular goitre.

Material and methods: The study included patients with multinodular goitre, who were referred for thyroidectomy. Ultrasound evaluation of suspicious nodules was performed with: improved B-mode (spatial compound imaging and differential tissue harmonics), dedicated mapping of microcalcifications, mapping of the nodule vessels, and strain elastography evaluated qualitatively and semi quantitatively.

Results: A total of 163 nodules in 124 patients with multinodular goitre were evaluated (147 benign and 16 cancers). Improved B-mode imaging was: 76.76% sensitive and 62.5% specific with AUC 0.740. Differentiating B-mode features were: shape — taller than wide OR 15.8, markedly hypoechoic OR 14.7, absence of cystic areas OR 6.6, absence of halo OR 5.0, and blurred/microlobulated margins OR 3.7. Addition of MicroPure imaging was 80.28% sensitive and 68.75% specific with AUC 0.771. MicroPure alone, power Doppler, and strain elastography were not statistically significant.

Conclusions: Among singular modes of ultrasound imaging, only improved B-mode imaging proved to have a significant role in differentiation of thyroid nodules in multinodular goitre. Additional gain was seen with the addition to B-mode of the mapping of microcalcifications with MicroPure imaging. Power Doppler and strain elastography did not prove to be useful techniques in multinodular goitre. (Endokrynol Pol 2016; 67 (2): 157–165)

Abstract

Introduction: To evaluate the relative value of technical ultrasound advances in differentiation of thyroid nodules in multinodular goitre.

Material and methods: The study included patients with multinodular goitre, who were referred for thyroidectomy. Ultrasound evaluation of suspicious nodules was performed with: improved B-mode (spatial compound imaging and differential tissue harmonics), dedicated mapping of microcalcifications, mapping of the nodule vessels, and strain elastography evaluated qualitatively and semi quantitatively.

Results: A total of 163 nodules in 124 patients with multinodular goitre were evaluated (147 benign and 16 cancers). Improved B-mode imaging was: 76.76% sensitive and 62.5% specific with AUC 0.740. Differentiating B-mode features were: shape — taller than wide OR 15.8, markedly hypoechoic OR 14.7, absence of cystic areas OR 6.6, absence of halo OR 5.0, and blurred/microlobulated margins OR 3.7. Addition of MicroPure imaging was 80.28% sensitive and 68.75% specific with AUC 0.771. MicroPure alone, power Doppler, and strain elastography were not statistically significant.

Conclusions: Among singular modes of ultrasound imaging, only improved B-mode imaging proved to have a significant role in differentiation of thyroid nodules in multinodular goitre. Additional gain was seen with the addition to B-mode of the mapping of microcalcifications with MicroPure imaging. Power Doppler and strain elastography did not prove to be useful techniques in multinodular goitre. (Endokrynol Pol 2016; 67 (2): 157–165)

Get Citation

Keywords

thyroid; goiter, nodular; ultrasonography; elasticity imaging techniques; ultrasonography, Doppler

About this article
Title

Differentiation of thyroid nodules in multinodular goiter with the application of technical ultrasound advances — initial results

Journal

Endokrynologia Polska

Issue

Vol 67, No 2 (2016)

Pages

157-165

Published online

2016-01-21

DOI

10.5603/EP.a2016.0026

Bibliographic record

Endokrynologia Polska 2016;67(2):157-165.

Keywords

thyroid
goiter
nodular
ultrasonography
elasticity imaging techniques
ultrasonography
Doppler

Authors

Bartosz Migda
Rafal Słapa
Jacek Bierca
Jadwiga Slowińska-Srzednicka
Anna Migda
Katarzyna Dobruch-Sobczak
Wiesław Jakubowski

Important: This website uses cookies.tanya dokter More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Via MedicaWydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl