open access

Vol 66, No 3 (2015)
Case report
Published online: 2015-07-01
Submitted: 2015-07-02
Accepted: 2015-07-02
Get Citation

Primary hyperparathyroidism in pregnancy — a diagnostic and therapeutic challenge

Joanna Rutkowska, Elżbieta Bandurska-Stankiewicz, Wojciech Matuszewski, Marek Gowkielewicz, Radosław Goraj, Dariusz Onichimowski
DOI: 10.5603/EP.2015.0034
·
Endokrynologia Polska 2015;66(3):270-274.

open access

Vol 66, No 3 (2015)
Case report
Published online: 2015-07-01
Submitted: 2015-07-02
Accepted: 2015-07-02

Abstract

Hypercalcaemia during pregnancy is uncommon, and mostly associated with primary hyperparathyroidism (pHPT). If unrecognised, it poses a significant risk for the mother and the foetus. Maternal symptoms include: hyperemesis, muscle weakness, pancreatitis, nephrolithiasis, bone disease, mental status changes, and hypercalcaemic crisis. Untreated disease complicates foetal development and foetal death is a significant risk. Our case illustrates the difficulty in detecting pHPT during pregnancy, serious complications connected with severe hypercalcaemia, and difficulties in preparing the patient for surgical treatment. Our review of the medical literature did not identify any previous case of a pregnant woman with hypercalcaemic crisis (total calcium 17 mg/dL, parathyroid hormone 2302 pg/mL), acute pancreatitis caused by pHPT, and with hyperthyroidism, who had undergone a successful surgical treatment. (Endokrynol Pol 2015; 66 (3): 270–274)

Abstract

Hypercalcaemia during pregnancy is uncommon, and mostly associated with primary hyperparathyroidism (pHPT). If unrecognised, it poses a significant risk for the mother and the foetus. Maternal symptoms include: hyperemesis, muscle weakness, pancreatitis, nephrolithiasis, bone disease, mental status changes, and hypercalcaemic crisis. Untreated disease complicates foetal development and foetal death is a significant risk. Our case illustrates the difficulty in detecting pHPT during pregnancy, serious complications connected with severe hypercalcaemia, and difficulties in preparing the patient for surgical treatment. Our review of the medical literature did not identify any previous case of a pregnant woman with hypercalcaemic crisis (total calcium 17 mg/dL, parathyroid hormone 2302 pg/mL), acute pancreatitis caused by pHPT, and with hyperthyroidism, who had undergone a successful surgical treatment. (Endokrynol Pol 2015; 66 (3): 270–274)

Get Citation

Keywords

primary hyperparathyroidism; hypercalcaemic crisis; pregnancy; acute pancreatitis

About this article
Title

Primary hyperparathyroidism in pregnancy — a diagnostic and therapeutic challenge

Journal

Endokrynologia Polska

Issue

Vol 66, No 3 (2015)

Pages

270-274

Published online

2015-07-01

DOI

10.5603/EP.2015.0034

Bibliographic record

Endokrynologia Polska 2015;66(3):270-274.

Keywords

primary hyperparathyroidism
hypercalcaemic crisis
pregnancy
acute pancreatitis

Authors

Joanna Rutkowska
Elżbieta Bandurska-Stankiewicz
Wojciech Matuszewski
Marek Gowkielewicz
Radosław Goraj
Dariusz Onichimowski

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