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Interesting coincidence of atypical TSH-secreting pituitary adenoma and chronic lymphocytic leukemia
open access
Abstract
Thyrotropin-secreting adenomas (TSH-oma) are very rare pituitary tumours. They are macroadenomas usually presenting with signs and symptoms of hyperthyroidism, and mass effects. They can co-secrete other hormones such as growth hormone or prolactin. Different malignancies, including haematological ones, are reported in patients with pituitary diseases. Chronic lymphocytic leukemia (CLL) occurs mostly in older patients, more often in males. CLL is associated with increased risk of second malignancies such as other blood neoplasms, skin and solid tumours. We present a successful neurosurgical outcome in a patient with an interesting coincidence of atypical TSH-oma and asymptomatic CLL. (Endokrynol Pol 2014; 65 (2): 144–147)
Abstract
Thyrotropin-secreting adenomas (TSH-oma) are very rare pituitary tumours. They are macroadenomas usually presenting with signs and symptoms of hyperthyroidism, and mass effects. They can co-secrete other hormones such as growth hormone or prolactin. Different malignancies, including haematological ones, are reported in patients with pituitary diseases. Chronic lymphocytic leukemia (CLL) occurs mostly in older patients, more often in males. CLL is associated with increased risk of second malignancies such as other blood neoplasms, skin and solid tumours. We present a successful neurosurgical outcome in a patient with an interesting coincidence of atypical TSH-oma and asymptomatic CLL. (Endokrynol Pol 2014; 65 (2): 144–147)
Keywords
TSH-oma; chronic lymphocytic leukemia


Title
Interesting coincidence of atypical TSH-secreting pituitary adenoma and chronic lymphocytic leukemia
Journal
Issue
Article type
Case report
Pages
144-147
Published online
2014-05-06
Page views
1692
Article views/downloads
2324
DOI
10.5603/EP.2014.0020
Bibliographic record
Endokrynol Pol 2014;65(2):144-147.
Keywords
TSH-oma
chronic lymphocytic leukemia
Authors
Marek Bolanowski
Grzegorz Zieliński
Aleksandra Jawiarczyk-Przybyłowska
Maria Maksymowicz
Stanisław Potoczek
Joanna Syrycka
Jan K. Podgórski