Vol 65, No 2 (2014)
Case report
Published online: 2014-05-06

open access

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Interesting coincidence of atypical TSH-secreting pituitary adenoma and chronic lymphocytic leukemia

Marek Bolanowski, Grzegorz Zieliński, Aleksandra Jawiarczyk-Przybyłowska, Maria Maksymowicz, Stanisław Potoczek, Joanna Syrycka, Jan K. Podgórski
DOI: 10.5603/EP.2014.0020
Endokrynol Pol 2014;65(2):144-147.


Thyrotropin-secreting adenomas (TSH-oma) are very rare pituitary tumours. They are macroadenomas usually presenting with signs and symptoms of hyperthyroidism, and mass effects. They can co-secrete other hormones such as growth hormone or prolactin. Different malignancies, including haematological ones, are reported in patients with pituitary diseases. Chronic lymphocytic leukemia (CLL) occurs mostly in older patients, more often in males. CLL is associated with increased risk of second malignancies such as other blood neoplasms, skin and solid tumours. We present a successful neurosurgical outcome in a patient with an interesting coincidence of atypical TSH-oma and asymptomatic CLL. (Endokrynol Pol 2014; 65 (2): 144–147)