open access
Aortopathies in Turner syndrome — new strategies for evaluation and treatment
open access
Abstract
Turner syndrome is a rare genetic disorder which impairs women’s growth, reproductive function, cardiovascular development and other functions. This syndrome has been proposed as an independent risk marker for cardiovascular disease. Despite this, life-threatening cardiovascular outcomes affecting young women are dismissed because of incomplete follow up. During assessment due to their smaller stature, it should be noted that, although the ascending aorta diameter is normal in absolute terms, after indexation for body size, patients with Turner syndrome may have a dilated aorta.
Based on recent guidelines and the latest studies, there is new evidence on the use of magnetic resonance imaging in diagnosing aortic lesions. New management possibilities of aortopathies have also been discussed. This approach should optimise medical care for women with Turner syndrome, but many areas of uncertainty still remain in the diagnosis and management of this syndrome, and new prospective studies are needed.
Abstract
Turner syndrome is a rare genetic disorder which impairs women’s growth, reproductive function, cardiovascular development and other functions. This syndrome has been proposed as an independent risk marker for cardiovascular disease. Despite this, life-threatening cardiovascular outcomes affecting young women are dismissed because of incomplete follow up. During assessment due to their smaller stature, it should be noted that, although the ascending aorta diameter is normal in absolute terms, after indexation for body size, patients with Turner syndrome may have a dilated aorta.
Based on recent guidelines and the latest studies, there is new evidence on the use of magnetic resonance imaging in diagnosing aortic lesions. New management possibilities of aortopathies have also been discussed. This approach should optimise medical care for women with Turner syndrome, but many areas of uncertainty still remain in the diagnosis and management of this syndrome, and new prospective studies are needed.
Keywords
Turner syndrome; aortopathies; management
About this articleTitle
Aortopathies in Turner syndrome — new strategies for evaluation and treatment
Journal
Issue
Article type
Review paper
Pages
58-65
Published online
2015-03-02
Page views
2003
Article views/downloads
2976
DOI
10.5603/EP.2015.0010
Pubmed
Bibliographic record
Endokrynol Pol 2015;66(1):58-65.
Keywords
Turner syndrome
aortopathies
management
Authors
Ruta Kriksciuniene
Rytas Ostrauskas
Birute Zilaitiene
