open access

Vol 65, No 3 (2014)
Case report
Published online: 2014-06-27
Submitted: 2014-02-12
Accepted: 2014-03-14
Get Citation

An atypical course of pancreatic neuroendocrine tumour manifesting as cardiac metastasis — a clinical case

Agnieszka Boratyn-Nowicka, Jolanta Blicharz-Dorniak, Ewa Wachuła, Jolanta Kunikowska, Beata Kos-Kudła
DOI: 10.5603/EP.2014.0032
·
Endokrynologia Polska 2014;65(3):232-239.

open access

Vol 65, No 3 (2014)
Case report
Published online: 2014-06-27
Submitted: 2014-02-12
Accepted: 2014-03-14

Abstract

This paper presents a ten-year course of the disease in a patient with pancreatic neuroendocrine tumour NEN G1, and with confirmed single, asymptomatic metastasis to the left cardiac ventricle. Initially, the cardiac metastasis was visible only on a positron emission tomography (PET) scan using gallium-68-labelled somatostatin analogue; the sensitivity of an echocardiography scan was lower. Despite the advanced stage of the disease, surgical excision of the cardiac metastasis was performed. The patient underwent a total of eight operations, and received chemotherapy, radiotherapy and somatostatin analogues. Currently, he is on a targeted therapy with everolimus. As a result of the treatment, the patient remains in a good general condition. This is the second described case of cardiac metastasis of PNEN. Using different methods of treatment in the case of generalised pancreatic neuroendocrine tumour with low proliferative potential, patients are offered the chance to prolong their survival and maintain a good quality of life.

Abstract

This paper presents a ten-year course of the disease in a patient with pancreatic neuroendocrine tumour NEN G1, and with confirmed single, asymptomatic metastasis to the left cardiac ventricle. Initially, the cardiac metastasis was visible only on a positron emission tomography (PET) scan using gallium-68-labelled somatostatin analogue; the sensitivity of an echocardiography scan was lower. Despite the advanced stage of the disease, surgical excision of the cardiac metastasis was performed. The patient underwent a total of eight operations, and received chemotherapy, radiotherapy and somatostatin analogues. Currently, he is on a targeted therapy with everolimus. As a result of the treatment, the patient remains in a good general condition. This is the second described case of cardiac metastasis of PNEN. Using different methods of treatment in the case of generalised pancreatic neuroendocrine tumour with low proliferative potential, patients are offered the chance to prolong their survival and maintain a good quality of life.

Get Citation

Keywords

pancreatic neuroendocrine neoplasm; somatostatin analogue; cardiac metastasis

About this article
Title

An atypical course of pancreatic neuroendocrine tumour manifesting as cardiac metastasis — a clinical case

Journal

Endokrynologia Polska

Issue

Vol 65, No 3 (2014)

Pages

232-239

Published online

2014-06-27

DOI

10.5603/EP.2014.0032

Bibliographic record

Endokrynologia Polska 2014;65(3):232-239.

Keywords

pancreatic neuroendocrine neoplasm
somatostatin analogue
cardiac metastasis

Authors

Agnieszka Boratyn-Nowicka
Jolanta Blicharz-Dorniak
Ewa Wachuła
Jolanta Kunikowska
Beata Kos-Kudła

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