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Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours)
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Abstract
An increased interest in gastro-entero-pancreatic neuroendocrine neoplasms (GEP NENs) has recently been observed. These are rare neoplasms and their detection in recent years has improved. Over 50% of GEP NENs are carcinoids, and they are usually found incidentally during surgery in the small intestine and appendix and at diagnosis in distant metastases, mainly to the liver. There is a need for co-operation between specialists in various disciplines of medicine in order to work out the diagnostic and therapeutic guidelines. In this publication, we present general recommendations of the Polish Network of Neuroendocrine Tumours for the management of patients with GEP NENs, developed at the Consensus Conference which took place in Kamień Śląski in April 2013. Members of the guidelines working groups were assigned sections of the 2008 guidance to update.
In the subsequent parts of this publication, we present the rules of diagnostic and therapeutic management of:
— neuroendocrine neoplasms of the stomach and duodenum (including gastrinoma);
— pancreatic neuroendocrine neoplasms;
— neuroendocrine neoplasms of the small intestine and the appendix;
— colorectal neuroendocrine neoplasms.
The proposed recommendations by Polish and foreign experts representing different fields of medicine (endocrinology, gastroenterology, surgery, oncology, nuclear medicine and pathology) will be helpful in the diagnosis and treatment of GEP NENs patients. (Endokrynol Pol 2013; 64 (6): 418–443)
Abstract
An increased interest in gastro-entero-pancreatic neuroendocrine neoplasms (GEP NENs) has recently been observed. These are rare neoplasms and their detection in recent years has improved. Over 50% of GEP NENs are carcinoids, and they are usually found incidentally during surgery in the small intestine and appendix and at diagnosis in distant metastases, mainly to the liver. There is a need for co-operation between specialists in various disciplines of medicine in order to work out the diagnostic and therapeutic guidelines. In this publication, we present general recommendations of the Polish Network of Neuroendocrine Tumours for the management of patients with GEP NENs, developed at the Consensus Conference which took place in Kamień Śląski in April 2013. Members of the guidelines working groups were assigned sections of the 2008 guidance to update.
In the subsequent parts of this publication, we present the rules of diagnostic and therapeutic management of:
— neuroendocrine neoplasms of the stomach and duodenum (including gastrinoma);
— pancreatic neuroendocrine neoplasms;
— neuroendocrine neoplasms of the small intestine and the appendix;
— colorectal neuroendocrine neoplasms.
The proposed recommendations by Polish and foreign experts representing different fields of medicine (endocrinology, gastroenterology, surgery, oncology, nuclear medicine and pathology) will be helpful in the diagnosis and treatment of GEP NENs patients. (Endokrynol Pol 2013; 64 (6): 418–443)
Keywords
gastro-entero-pancreatic neuroendocrine neoplasm; diagnosis; therapy
About this articleTitle
Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours)
Journal
Issue
Article type
Review paper
Pages
418-443
Published online
2013-12-31
Page views
7375
Article views/downloads
6841
DOI
10.5603/EP.2013.0028
Bibliographic record
Endokrynol Pol 2013;64(6):418-443.
Keywords
gastro-entero-pancreatic neuroendocrine neoplasm
diagnosis
therapy
Authors
Beata Kos-Kudła
Jolanta Blicharz-Dorniak
Daria Handkiewicz-Junak
Barbara Jarząb
Michał Jarząb
Jolanta Kunikowska
Katarzyna Kuśnierz
Robert Król
Leszek Królicki
Maciej Krzakowski
Anna Nasierowska-Guttmejer
Ewa Nowakowska-Duława
Waldemar Patkowski
Andrzej W. Szawłowski
other participants of the Consensus Conference (affiliations at the end of this section):
Elżbieta Andrysiak-Mamos
Tomasz Bednarczuk
Marek Bolanowski
Andrzej Cichocki
Jarosław Ćwikła
Andrzej Deptała
Wanda Foltyn
Marek Hartleb
Alicja Hubalewska-Dydejczyk
Barbara Jarząb
Arkadiusz Jeziorski
Dariusz Kajdaniuk
Grzegorz Kamiński
Aldona Kowalska
Paweł Lampe
Dariusz Lange
Anna Lewczuk
Magdalena Londzin-Olesik
Przemysław Majewski
Bogdan Marek
Gabriela Mełeń-Mucha
Andrzej Nowak
Joanna Pilch-Kowalczyk
Violetta Rosiek
Marek Ruchała
Sławomir Rudzki
Philippe Ruszniewski
Grażyna Rydzewska
Anna Sowa-Staszczak
Teresa Starzyńska
Katarzyna Steinhof-Radwańska
Janusz Strzelczyk
Wojciech Zajęcki
Piotr Zdunowski
Anna Zemczak
