open access

Vol 64, No 6 (2013)
Postgraduate education
Published online: 2013-12-31
Submitted: 2014-01-03
Accepted: 2014-01-03
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Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours)

Beata Kos-Kudła, Jolanta Blicharz-Dorniak, Daria Handkiewicz-Junak, Barbara Jarząb, Michał Jarząb, Jolanta Kunikowska, Katarzyna Kuśnierz, Robert Król, Leszek Królicki, Maciej Krzakowski, Anna Nasierowska-Guttmejer, Ewa Nowakowska-Duława, Waldemar Patkowski, Andrzej W. Szawłowski, other participants of the Consensus Conference (affiliations at the end of this section):, Elżbieta Andrysiak-Mamos, Tomasz Bednarczuk, Marek Bolanowski, Andrzej Cichocki, Jarosław Ćwikła, Andrzej Deptała, Wanda Foltyn, Marek Hartleb, Alicja Hubalewska-Dydejczyk, Barbara Jarząb, Arkadiusz Jeziorski, Dariusz Kajdaniuk, Grzegorz Kamiński, Aldona Kowalska, Paweł Lampe, Dariusz Lange, Anna Lewczuk, Magdalena Londzin-Olesik, Przemysław Majewski, Bogdan Marek, Gabriela Mełeń-Mucha, Andrzej Nowak, Joanna Pilch-Kowalczyk, Violetta Rosiek, Marek Ruchała, Sławomir Rudzki, Philippe Ruszniewski, Grażyna Rydzewska, Anna Sowa-Staszczak, Teresa Starzyńska, Katarzyna Steinhof-Radwańska, Janusz Strzelczyk, Wojciech Zajęcki, Piotr Zdunowski, Anna Zemczak
DOI: 10.5603/EP.2013.0028
·
Endokrynologia Polska 2013;64(6):418-443.

open access

Vol 64, No 6 (2013)
Postgraduate education
Published online: 2013-12-31
Submitted: 2014-01-03
Accepted: 2014-01-03

Abstract

An increased interest in gastro-entero-pancreatic neuroendocrine neoplasms (GEP NENs) has recently been observed. These are rare neoplasms and their detection in recent years has improved. Over 50% of GEP NENs are carcinoids, and they are usually found incidentally during surgery in the small intestine and appendix and at diagnosis in distant metastases, mainly to the liver. There is a need for co-operation between specialists in various disciplines of medicine in order to work out the diagnostic and therapeutic guidelines. In this publication, we present general recommendations of the Polish Network of Neuroendocrine Tumours for the management of patients with GEP NENs, developed at the Consensus Conference which took place in Kamień Śląski in April 2013. Members of the guidelines working groups were assigned sections of the 2008 guidance to update.

In the subsequent parts of this publication, we present the rules of diagnostic and therapeutic management of:

— neuroendocrine neoplasms of the stomach and duodenum (including gastrinoma);

— pancreatic neuroendocrine neoplasms;

— neuroendocrine neoplasms of the small intestine and the appendix;

— colorectal neuroendocrine neoplasms.

The proposed recommendations by Polish and foreign experts representing different fields of medicine (endocrinology, gastroenterology, surgery, oncology, nuclear medicine and pathology) will be helpful in the diagnosis and treatment of GEP NENs patients. (Endokrynol Pol 2013; 64 (6): 418–443)

Abstract

An increased interest in gastro-entero-pancreatic neuroendocrine neoplasms (GEP NENs) has recently been observed. These are rare neoplasms and their detection in recent years has improved. Over 50% of GEP NENs are carcinoids, and they are usually found incidentally during surgery in the small intestine and appendix and at diagnosis in distant metastases, mainly to the liver. There is a need for co-operation between specialists in various disciplines of medicine in order to work out the diagnostic and therapeutic guidelines. In this publication, we present general recommendations of the Polish Network of Neuroendocrine Tumours for the management of patients with GEP NENs, developed at the Consensus Conference which took place in Kamień Śląski in April 2013. Members of the guidelines working groups were assigned sections of the 2008 guidance to update.

In the subsequent parts of this publication, we present the rules of diagnostic and therapeutic management of:

— neuroendocrine neoplasms of the stomach and duodenum (including gastrinoma);

— pancreatic neuroendocrine neoplasms;

— neuroendocrine neoplasms of the small intestine and the appendix;

— colorectal neuroendocrine neoplasms.

The proposed recommendations by Polish and foreign experts representing different fields of medicine (endocrinology, gastroenterology, surgery, oncology, nuclear medicine and pathology) will be helpful in the diagnosis and treatment of GEP NENs patients. (Endokrynol Pol 2013; 64 (6): 418–443)

Get Citation

Keywords

gastro-entero-pancreatic neuroendocrine neoplasm; diagnosis; therapy

About this article
Title

Diagnostic and therapeutic guidelines for gastro-entero-pancreatic neuroendocrine neoplasms (recommended by the Polish Network of Neuroendocrine Tumours)

Journal

Endokrynologia Polska

Issue

Vol 64, No 6 (2013)

Pages

418-443

Published online

2013-12-31

DOI

10.5603/EP.2013.0028

Bibliographic record

Endokrynologia Polska 2013;64(6):418-443.

Keywords

gastro-entero-pancreatic neuroendocrine neoplasm
diagnosis
therapy

Authors

Beata Kos-Kudła
Jolanta Blicharz-Dorniak
Daria Handkiewicz-Junak
Barbara Jarząb
Michał Jarząb
Jolanta Kunikowska
Katarzyna Kuśnierz
Robert Król
Leszek Królicki
Maciej Krzakowski
Anna Nasierowska-Guttmejer
Ewa Nowakowska-Duława
Waldemar Patkowski
Andrzej W. Szawłowski
other participants of the Consensus Conference (affiliations at the end of this section):
Elżbieta Andrysiak-Mamos
Tomasz Bednarczuk
Marek Bolanowski
Andrzej Cichocki
Jarosław Ćwikła
Andrzej Deptała
Wanda Foltyn
Marek Hartleb
Alicja Hubalewska-Dydejczyk
Barbara Jarząb
Arkadiusz Jeziorski
Dariusz Kajdaniuk
Grzegorz Kamiński
Aldona Kowalska
Paweł Lampe
Dariusz Lange
Anna Lewczuk
Magdalena Londzin-Olesik
Przemysław Majewski
Bogdan Marek
Gabriela Mełeń-Mucha
Andrzej Nowak
Joanna Pilch-Kowalczyk
Violetta Rosiek
Marek Ruchała
Sławomir Rudzki
Philippe Ruszniewski
Grażyna Rydzewska
Anna Sowa-Staszczak
Teresa Starzyńska
Katarzyna Steinhof-Radwańska
Janusz Strzelczyk
Wojciech Zajęcki
Piotr Zdunowski
Anna Zemczak

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