open access

Vol 64, No 5 (2013)
Postgraduate education
Published online: 2013-11-01
Submitted: 2013-11-04
Accepted: 2013-11-04
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Reimbursement of metformin for polycystic ovary syndrome

Andrzej Milewicz
DOI: 10.5603/EP.2013.0025
·
Endokrynologia Polska 2013;64(5):409-414.

open access

Vol 64, No 5 (2013)
Postgraduate education
Published online: 2013-11-01
Submitted: 2013-11-04
Accepted: 2013-11-04

Abstract

The latest list of reimbursed medicines includes, as a new addition, metformin for the treatment of polycystic ovary syndrome (PCOS),
which is extremely important for practicing physicians. While this paper briefly summarises the current state of knowledge on PCOS,
its main aim is to remind the reader about the effectiveness of metformin in women with PCOS in controlling glycaemia, increasing
tissue sensitivity to insulin and affecting endothelial function, vascular inflammation, lipid profile and other risk factors of atherosclerosis,
which suggests its cardioprotective effects. The paper also discusses the clinical effect of metformin relative to hyperandrogenism,
menstrual cycle disorders and ovulation induction. The paper concludes with an algorithm for the diagnosis and management of PCOS.

(Endokrynol Pol 2013; 64 (5): 409–414)

Abstract

The latest list of reimbursed medicines includes, as a new addition, metformin for the treatment of polycystic ovary syndrome (PCOS),
which is extremely important for practicing physicians. While this paper briefly summarises the current state of knowledge on PCOS,
its main aim is to remind the reader about the effectiveness of metformin in women with PCOS in controlling glycaemia, increasing
tissue sensitivity to insulin and affecting endothelial function, vascular inflammation, lipid profile and other risk factors of atherosclerosis,
which suggests its cardioprotective effects. The paper also discusses the clinical effect of metformin relative to hyperandrogenism,
menstrual cycle disorders and ovulation induction. The paper concludes with an algorithm for the diagnosis and management of PCOS.

(Endokrynol Pol 2013; 64 (5): 409–414)

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Keywords

PCOS; metabolic abnormalities; metformin

About this article
Title

Reimbursement of metformin for polycystic ovary syndrome

Journal

Endokrynologia Polska

Issue

Vol 64, No 5 (2013)

Pages

409-414

Published online

2013-11-01

DOI

10.5603/EP.2013.0025

Bibliographic record

Endokrynologia Polska 2013;64(5):409-414.

Keywords

PCOS
metabolic abnormalities
metformin

Authors

Andrzej Milewicz

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