open access

Vol 6, No 3 (2017)
REVIEW ARTICLES
Published online: 2017-09-29
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Diabetic enteropathy — still undefeated?

Aleksandra Tomaszewska, Beata Mrozikiewicz-Rakowska, Leszek Czupryniak
DOI: 10.5603/DK.2017.0017
·
Clinical Diabetology 2017;6(3):105-110.

open access

Vol 6, No 3 (2017)
REVIEW ARTICLES
Published online: 2017-09-29

Abstract

Diabetic enteropathy is a specific diabetic complica­tion. It could be presented as constipations, diarrhoea or faecal incontinence. The aetiology is multifactorial. The main role is attributed to irreversible autonomic neuropathy, which often coexists with peripheral sen­sorimotor neuropathy. Nowadays, enteropathy is diag­nosed after exclusion of other causes, like coeliac dis­ease, hypo- or hyperthyroidism, inflammatory bowel disease, small intestinal bacterial overgrowth, exocrine pancreatic insufficiency and adverse drug reaction. The article presents new reports about enteropathy reversibility after simultaneous pancreas-kidney trans­plantation in patients with abnormal levels of IGF-1 and IGFBP3. It provides new data on pathogenesis of enteropathy and presents new diagnostic and thera­peutic approaches. (Clin Diabetol 2017; 6, 3: 105–110)

Abstract

Diabetic enteropathy is a specific diabetic complica­tion. It could be presented as constipations, diarrhoea or faecal incontinence. The aetiology is multifactorial. The main role is attributed to irreversible autonomic neuropathy, which often coexists with peripheral sen­sorimotor neuropathy. Nowadays, enteropathy is diag­nosed after exclusion of other causes, like coeliac dis­ease, hypo- or hyperthyroidism, inflammatory bowel disease, small intestinal bacterial overgrowth, exocrine pancreatic insufficiency and adverse drug reaction. The article presents new reports about enteropathy reversibility after simultaneous pancreas-kidney trans­plantation in patients with abnormal levels of IGF-1 and IGFBP3. It provides new data on pathogenesis of enteropathy and presents new diagnostic and thera­peutic approaches. (Clin Diabetol 2017; 6, 3: 105–110)

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Keywords

diabetes, diabetic enteropathy, diabetic autonomic neuropathy, diabetic diarrhoea, faecal incontinence

About this article
Title

Diabetic enteropathy — still undefeated?

Journal

Clinical Diabetology

Issue

Vol 6, No 3 (2017)

Pages

105-110

Published online

2017-09-29

DOI

10.5603/DK.2017.0017

Bibliographic record

Clinical Diabetology 2017;6(3):105-110.

Keywords

diabetes
diabetic enteropathy
diabetic autonomic neuropathy
diabetic diarrhoea
faecal incontinence

Authors

Aleksandra Tomaszewska
Beata Mrozikiewicz-Rakowska
Leszek Czupryniak

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