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Vol 6, No 2 (2017)
Original articles (submitted)
Published online: 2017-08-03
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The effects of a single bout of submaximal exercise on rheological properties of the blood in children with type 1 diabetes mellitus

Dorota Gazurek, Magdalena Kępińska, Aleksandra Kulis, Anna Koszela
DOI: 10.5603/DK.2017.0011
·
Clinical Diabetology 2017;6(2):65-69.

open access

Vol 6, No 2 (2017)
Original articles (submitted)
Published online: 2017-08-03

Abstract

Background. The aim of this study was to analyze the effects of a single bout of submaximal exercise on rheological properties of the blood children with type 1 diabetes mellitus and healthy controls.

Material and methods. The study included 18 children in the age before puberty, with type 1 diabetes, both newly diagnosed (Group 1, n = 11) and with the diagnosis established at least five years earlier (Group 2, n = 7). Group 3 (n = 11) was comprised of age- and sex-matched healthy controls. Children from all the groups were subjected to progressive submaximal exercise test on a cycle ergometer. Prior to the exercise and after the test, rheological parameters of peripheral blood erythrocytes: elongation index (EI), amplitude of aggregation (AMP), half time of total aggregation (T1/2) and aggregation index (AI) were determined.

Results. No significant differences were found between the pre- and post-exercise values of erythrocyte aggregability measures (AI, T1/2 and AMP) and EI values at 0.30–59.07 Pa for any of the study groups.

Conclusions. These results suggest that a single bout of physical exercise exerts no unfavorable effect on erythrocyte rheology in children with type 1 diabetes mellitus. Also time elapsed since the diagnosis of type 1 diabetes mellitus does not influence rheological properties of the blood.

Abstract

Background. The aim of this study was to analyze the effects of a single bout of submaximal exercise on rheological properties of the blood children with type 1 diabetes mellitus and healthy controls.

Material and methods. The study included 18 children in the age before puberty, with type 1 diabetes, both newly diagnosed (Group 1, n = 11) and with the diagnosis established at least five years earlier (Group 2, n = 7). Group 3 (n = 11) was comprised of age- and sex-matched healthy controls. Children from all the groups were subjected to progressive submaximal exercise test on a cycle ergometer. Prior to the exercise and after the test, rheological parameters of peripheral blood erythrocytes: elongation index (EI), amplitude of aggregation (AMP), half time of total aggregation (T1/2) and aggregation index (AI) were determined.

Results. No significant differences were found between the pre- and post-exercise values of erythrocyte aggregability measures (AI, T1/2 and AMP) and EI values at 0.30–59.07 Pa for any of the study groups.

Conclusions. These results suggest that a single bout of physical exercise exerts no unfavorable effect on erythrocyte rheology in children with type 1 diabetes mellitus. Also time elapsed since the diagnosis of type 1 diabetes mellitus does not influence rheological properties of the blood.

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Keywords

physical exercise, blood rheology, erythrocyte membrane, diabetes mellitus, pediatrics

About this article
Title

The effects of a single bout of submaximal exercise on rheological properties of the blood in children with type 1 diabetes mellitus

Journal

Clinical Diabetology

Issue

Vol 6, No 2 (2017)

Pages

65-69

Published online

2017-08-03

DOI

10.5603/DK.2017.0011

Bibliographic record

Clinical Diabetology 2017;6(2):65-69.

Keywords

physical exercise
blood rheology
erythrocyte membrane
diabetes mellitus
pediatrics

Authors

Dorota Gazurek
Magdalena Kępińska
Aleksandra Kulis
Anna Koszela

References (19)
  1. Desouky OS, Selim NS, El-Bakrawy EM. and El-Marakby SM. Biophysical characterization of beta-thalassemic red blood cells. Cell Biochem Biophys. 2009; 55: 45–53.
  2. American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 33. ; 1(Suppl 2010): 62–69.
  3. Szadkowska A, Markuszewski L, Bodalski J. Udział insulinosekrecji i insulinooporności w kształtowaniu obrazu klinicznego świeżo rozpoznanej cukrzycy u dzieci Med Wieku Rozwoj. 2005; 9: 223–234.
  4. Hussain A. Diabetes mellitus, type 1. emedicinemedscapecom 2007.
  5. Lamb W. Diabetes mellitus, type 1. emedicinemedscapecom 2009.
  6. Jarosz-Chobot P, Polanska J, Szadkowska A, et al. Rapid increase in the incidence of type 1 diabetes in Polish children from 1989 to 2004, and predictions for 2010 to 2025. Diabetologia. 2011; 54(3): 508–515.
  7. Admon G, Weinstein Y, Falk B, et al. Exercise with and without an insulin pump among children and adolescents with type 1 diabetes mellitus. Pediatrics. 2005; 116(3): e348–e355.
  8. Jankowiak B, Jakimiuk U, Sierakowska M, et al. and Baranowska A. Zakres edukacji zdrowotnej chorych na cukrzycę typu 1 w odniesieniu do ich wiedzy o chorobie. Ann Acad Med Siles. 2006; 60: 476–481.
  9. Shin KiOk, Moritani T, Woo J, et al. Exercise training improves cardiac autonomic nervous system activity in type 1 diabetic children. J Phys Ther Sci. 2014; 26(1): 111–115.
  10. Toni S, Reali MF, Barni F, et al. and Festini F. Managing insulin therapy during exercise in type 1 diabetes mellitus, Acta Biomed 77. ; 1(Suppl 2006): 34–40.
  11. Yardley J, Mollard R, MacIntosh A, et al. Vigorous intensity exercise for glycemic control in patients with type 1 diabetes. Can J Diabetes. 2013; 37(6): 427–432.
  12. Dąbrowski Z. Hemorheology. Diagnostyka Laboratoryjna. 2010; 46: 365–369.
  13. DeMarco HM, Sucher KP, Cisar CJ, et al. Pre-exercise carbohydrate meals: application of glycemic index. Med Sci Sports Exerc. 1999; 31(1): 164–170.
  14. Bilski J, Teległów A, Pokorski J, et al. Effects of a meal on the hemorheologic responses to exercise in young males. Biomed Res Int. 2014; 2014: 862968.
  15. van der Brug GE, Peters HP, Hardeman MR, et al. Hemorheological response to prolonged exercise--no effects of different kinds of feedings. Int J Sports Med. 1995; 16(4): 231–237.
  16. Monnier JF, Benhaddad AA, Micallef JP, et al. Relationships between blood viscosity and insulin-like growth factor I status in athletes. Clin Hemorheol Microcirc. 2000; 22(4): 277–286.
  17. Shin S, Ku Y, Babu N, et al. Erythrocyte deformability and its variation in diabetes mellitus. Indian J Exp Biol. 2007; 45(1): 121–128.
  18. Koszela A, Szyguła Z. Impact the clinical course of type 1 diabetes mellitus in competitive sports. A case study. Medicina Sportiva Practica. 2011; 12: 95–98.
  19. Tansey MJ, Tsalikian E, Beck RW, et al. Diabetes Research in Children Network (DirecNet) Study Group. The effects of aerobic exercise on glucose and counterregulatory hormone concentrations in children with type 1 diabetes. Diabetes Care. 2006; 29(1): 20–25.

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