open access

Vol 21, No 4 (2014)
Original articles
Published online: 2014-08-29
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Resting heart rate at hospital admission and its relation to hospital outcome in patients with heart failure

Agnieszka Kapłon-Cieślicka, Paweł Balsam, Krzysztof Ozierański, Agata Tymińska, Michał Peller, Michalina Galas, Marcin Wyzgał, Michał Marchel, Jarosław Drożdż, Grzegorz Opolski
DOI: 10.5603/CJ.a2013.0147
·
Cardiol J 2014;21(4):425-433.

open access

Vol 21, No 4 (2014)
Original articles
Published online: 2014-08-29

Abstract

Background: Resting heart rate (HR) has been proven to influence long-term prognosis in patients with chronic heart failure (HF). The aim of this study was to assess the relationship between resting HR at hospital admission and hospital outcome in patients with HF.

Methods: The study included Polish patients admitted to hospital due to HF who agreed to participate in Heart Failure Pilot Survey of the European Society of Cardiology.

Results: The final analysis included 598 patients. Median HR at hospital admission was 80 bpm. In univariate analyses, higher HR at admission was associated with more frequent use of inotropic support (p = 0.0462) and diuretics (p = 0.0426), worse clinical (New York Heart Association — NYHA) status at discharge (p = 0.0483), longer hospital stay (p = 0.0303) and higher in-hospital mortality (p = 0.003). Compared to patients who survived, patients who died during hospitalization (n = 21; 3.5%) were older, more often had a history of stroke or tran­sient ischemic attack and were characterized by higher NYHA class, higher HR at admission, lower systolic and diastolic blood pressure at admission, lower ejection fraction, lower glomeru­lar filtration rate, and lower natrium and hemoglobin concentrations at hospital admission. In multivariate analysis, higher HR at admission (OR 1.594 [per 10 bpm]; 95% CI 1.061–2.395; p = 0.0248) and lower natrium concentration at admission (OR 0.767 [per 1 mmol/L]; 95% CI 0.618–0.952; p = 0.0162) were the only independent predictors of in-hospital mortality.

Conclusions: In patients with HF, higher resting HR at hospital admission is associated with increased in-hospital mortality.

Abstract

Background: Resting heart rate (HR) has been proven to influence long-term prognosis in patients with chronic heart failure (HF). The aim of this study was to assess the relationship between resting HR at hospital admission and hospital outcome in patients with HF.

Methods: The study included Polish patients admitted to hospital due to HF who agreed to participate in Heart Failure Pilot Survey of the European Society of Cardiology.

Results: The final analysis included 598 patients. Median HR at hospital admission was 80 bpm. In univariate analyses, higher HR at admission was associated with more frequent use of inotropic support (p = 0.0462) and diuretics (p = 0.0426), worse clinical (New York Heart Association — NYHA) status at discharge (p = 0.0483), longer hospital stay (p = 0.0303) and higher in-hospital mortality (p = 0.003). Compared to patients who survived, patients who died during hospitalization (n = 21; 3.5%) were older, more often had a history of stroke or tran­sient ischemic attack and were characterized by higher NYHA class, higher HR at admission, lower systolic and diastolic blood pressure at admission, lower ejection fraction, lower glomeru­lar filtration rate, and lower natrium and hemoglobin concentrations at hospital admission. In multivariate analysis, higher HR at admission (OR 1.594 [per 10 bpm]; 95% CI 1.061–2.395; p = 0.0248) and lower natrium concentration at admission (OR 0.767 [per 1 mmol/L]; 95% CI 0.618–0.952; p = 0.0162) were the only independent predictors of in-hospital mortality.

Conclusions: In patients with HF, higher resting HR at hospital admission is associated with increased in-hospital mortality.

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Keywords

heart rate, heart failure, prognosis, in-hospital mortality, hyponatremia

About this article
Title

Resting heart rate at hospital admission and its relation to hospital outcome in patients with heart failure

Journal

Cardiology Journal

Issue

Vol 21, No 4 (2014)

Pages

425-433

Published online

2014-08-29

DOI

10.5603/CJ.a2013.0147

Bibliographic record

Cardiol J 2014;21(4):425-433.

Keywords

heart rate
heart failure
prognosis
in-hospital mortality
hyponatremia

Authors

Agnieszka Kapłon-Cieślicka
Paweł Balsam
Krzysztof Ozierański
Agata Tymińska
Michał Peller
Michalina Galas
Marcin Wyzgał
Michał Marchel
Jarosław Drożdż
Grzegorz Opolski

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