open access

Vol 21, No 4 (2014)
Original articles
Published online: 2014-08-29
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Evaluation of the effect of mitral stenosis severity on the left ventricular systolic function using isovolumic myocardial acceleration

Mehmet Erturk, Hale Unal Aksu, Omer Celik, Fatih Uzun, Ozgur Akgul, Hamdi Pusuroglu, Ali Kemal Kalkan, Ahmet Arif Yalcin, Muhammet Hulusi Satilmisoglu, Mustafa Kemal Erol
DOI: 10.5603/CJ.a2013.0114
·
Cardiol J 2014;21(4):442-448.

open access

Vol 21, No 4 (2014)
Original articles
Published online: 2014-08-29

Abstract

Background: Isovolumic acceleration (IVA) is a new tissue Doppler parameter in the as­sessment of systolic function of both left and right ventricles. It remains unaffected with the changes in pre- and after-load within the physiological range. The aim of our study was to assess the effect of mitral stenosis degree, which is determined by echocardiography, on the left ventricular (LV) function using IVA.

Methods: A total number of 62 patients with mitral stenosis (MS) and 32 healthy controls were examined. The severity of MS (mild, moderate, and severe) was determined on the basis of mitral valve area (MVA) and the mean diastolic mitral gradient findings. The peak myocardial velocities during isovolumic contraction, systole, early diastole and late diastole were measured by using tissue Doppler imaging (TDI).

Results: All TDI-derived global LV basal wall systolic (peak myocardial isovolumic contra­ction velocity, peak myocardial systolic velocity and IVA), and diastolic velocities (peak early and late diastolic velocities) were significantly decreased in the patients with MS, compared to the healthy patients (p < 0.001, for all). However, IVA was not different when the degree of MS was evaluated (p = 0.114). In addition, IVA was not correlated with the MVA (r = 0.185, p = 0.150).

Conclusions: Left ventricular function is impaired in patients with MS regardless of the severity of the disease.

Abstract

Background: Isovolumic acceleration (IVA) is a new tissue Doppler parameter in the as­sessment of systolic function of both left and right ventricles. It remains unaffected with the changes in pre- and after-load within the physiological range. The aim of our study was to assess the effect of mitral stenosis degree, which is determined by echocardiography, on the left ventricular (LV) function using IVA.

Methods: A total number of 62 patients with mitral stenosis (MS) and 32 healthy controls were examined. The severity of MS (mild, moderate, and severe) was determined on the basis of mitral valve area (MVA) and the mean diastolic mitral gradient findings. The peak myocardial velocities during isovolumic contraction, systole, early diastole and late diastole were measured by using tissue Doppler imaging (TDI).

Results: All TDI-derived global LV basal wall systolic (peak myocardial isovolumic contra­ction velocity, peak myocardial systolic velocity and IVA), and diastolic velocities (peak early and late diastolic velocities) were significantly decreased in the patients with MS, compared to the healthy patients (p < 0.001, for all). However, IVA was not different when the degree of MS was evaluated (p = 0.114). In addition, IVA was not correlated with the MVA (r = 0.185, p = 0.150).

Conclusions: Left ventricular function is impaired in patients with MS regardless of the severity of the disease.

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Keywords

isovolumic acceleration, mitral stenosis, left ventricular function, tissue Doppler imaging

About this article
Title

Evaluation of the effect of mitral stenosis severity on the left ventricular systolic function using isovolumic myocardial acceleration

Journal

Cardiology Journal

Issue

Vol 21, No 4 (2014)

Pages

442-448

Published online

2014-08-29

DOI

10.5603/CJ.a2013.0114

Bibliographic record

Cardiol J 2014;21(4):442-448.

Keywords

isovolumic acceleration
mitral stenosis
left ventricular function
tissue Doppler imaging

Authors

Mehmet Erturk
Hale Unal Aksu
Omer Celik
Fatih Uzun
Ozgur Akgul
Hamdi Pusuroglu
Ali Kemal Kalkan
Ahmet Arif Yalcin
Muhammet Hulusi Satilmisoglu
Mustafa Kemal Erol

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