Vol 20, No 4 (2013)
Original articles
Published online: 2013-07-26

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The Atrial Fibrillation in Turkey: Epidemiologic Registry (AFTER)

Faruk Ertas, Nihan Kahya Eren, Hasan Kaya, Alpay Aribas, Goksel Acar, Mehmet Kanadasi, Selcuk Gedik, Mustafa Oylumlu, Murat Yuksel, Mehmet Siddik Ulgen
DOI: 10.5603/CJ.a2013.0055
Cardiol J 2013;20(4):447-452.

Abstract

Background: AFTER (Atrial Fibrillation in Turkey: Epidemiologic Registry) is a prospective,
multicenter study designed with the aim of describing the prevalence and epidemiology of
AF practice in Turkey. This study aims to evaluate stroke risk in non-valvular atrial fi brillation
(AF) and anticoagulant drug utilization within conformity to AF guidelines.

Methods: Patients were recruited in 17 referral hospitals refl ecting all the population of
7 geographical regions of Turkey. 2242 consecutive patients who had been admitted with AF
on ECG were included in the study. 1745 of these patients, who had non-valvular AF, were
included in the statistical evaluation. Stroke risk was evaluated with the CHA2DS2-VASc score.

Results: The average age of participants was determined to be 69.2 ± 11.5 years (56%
female). Persistent-permanent AF was found to be the most common type of non-valvular
AF (78%). The most common comorbid disorder was hypertension (73%). It was found that
oral anticoagulant therapy was used by 40% of all patients, 37% of whom had effective INR
(2.0–3.0). Upon multivariate analysis, age was found to be the only independent predictor
of stroke among the variables’ effects on thromboembolic events that created CHA2DS2-VASc
abbreviations (OR 1.026, p < 0.001).

Conclusions: These results suggest that stroke risk scores should be thoroughly heeded
based on guidelines, and that anticoagulation must be applied according to their guidance.