open access

Vol 19, No 3 (2012)
Original articles
Published online: 2012-05-28
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Relationship between psychosocial status, diabetes mellitus, and left ventricular systolic function in patients with stable multivessel coronary artery disease

Orhan Dogdu, Mikail Yarlioglues, Mehmet Gungor Kaya, Idris Ardic, Mahmut Akpek, Omer Senarslan, Deniz Elcik, Omer Sahin, Erol Tulumen, Bekir Calapkorur, Nihat Kalay
Cardiol J 2012;19(3):249-255.

open access

Vol 19, No 3 (2012)
Original articles
Published online: 2012-05-28

Abstract

Background: Negative emotional conditions contribute to the development of coronary artery disease (CAD). Depression and anxiety are prognostic factors in patients with CAD. The aim of our study was to investigate the association between emotional conditions and left ventricular (LV) systolic functions in CAD.
Methods:
168 patients (102 men, 66 women, mean age 66.3 ± 9.9 years) with stable angina and multivessel disease (MVD) were included in the study. According to the LV ejection fraction (LVEF) in echocardiography, patients were divided into two groups, the preserved group (LVEF > 50%), and the impaired group (LVEF < 50%). The preserved group consisted of 94 patients and the impaired group consisted of 74 patients. Emotional status was evaluated using the Hamilton Depression (HAM-D), Hamilton Anxiety (HAM-A), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) scores.
Results:
The prevalence of diabetes mellitus (DM) was significantly higher in the impaired group than in the preserved group (29.8% vs 56.8%, p < 0.01). The HAM-D, HAM-A, BAI and BDI scores were higher in the impaired group compared to the preserved group (HAM-D: 12.1 ± 3.3 vs 14.5 ± 2.3, p = 0.03; HAM-A: 12.7 ± 3.4 vs 14.3 ± 2.2, p = 0.01; BAI: 18.6 ± ± 6.4 vs 22.1 ± 6.6, p = 0.01 and BDI: 13.9 ± 2.5 vs 17.2 ± 2.0, p = 0.002, respectively). In multivariate analysis, BDI scores (odds ratio [OR]: 2.197, < 95% confidence interval [CI] 1.101–4.387; p = 0.026), HAM-A scores (OR: 1.912, < 95% Cl 1.092–2.974; p = 0.041) and DM (OR: 2.610, < 95% Cl 1.313–5.183; p = 0.006) were important risk factors for LV dysfunction in stable patients with MVD.
Conclusions: This study demonstrated that emotional status and DM are factors associated with impaired LV systolic function in patients with stable CAD.

Abstract

Background: Negative emotional conditions contribute to the development of coronary artery disease (CAD). Depression and anxiety are prognostic factors in patients with CAD. The aim of our study was to investigate the association between emotional conditions and left ventricular (LV) systolic functions in CAD.
Methods:
168 patients (102 men, 66 women, mean age 66.3 ± 9.9 years) with stable angina and multivessel disease (MVD) were included in the study. According to the LV ejection fraction (LVEF) in echocardiography, patients were divided into two groups, the preserved group (LVEF > 50%), and the impaired group (LVEF < 50%). The preserved group consisted of 94 patients and the impaired group consisted of 74 patients. Emotional status was evaluated using the Hamilton Depression (HAM-D), Hamilton Anxiety (HAM-A), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) scores.
Results:
The prevalence of diabetes mellitus (DM) was significantly higher in the impaired group than in the preserved group (29.8% vs 56.8%, p < 0.01). The HAM-D, HAM-A, BAI and BDI scores were higher in the impaired group compared to the preserved group (HAM-D: 12.1 ± 3.3 vs 14.5 ± 2.3, p = 0.03; HAM-A: 12.7 ± 3.4 vs 14.3 ± 2.2, p = 0.01; BAI: 18.6 ± ± 6.4 vs 22.1 ± 6.6, p = 0.01 and BDI: 13.9 ± 2.5 vs 17.2 ± 2.0, p = 0.002, respectively). In multivariate analysis, BDI scores (odds ratio [OR]: 2.197, < 95% confidence interval [CI] 1.101–4.387; p = 0.026), HAM-A scores (OR: 1.912, < 95% Cl 1.092–2.974; p = 0.041) and DM (OR: 2.610, < 95% Cl 1.313–5.183; p = 0.006) were important risk factors for LV dysfunction in stable patients with MVD.
Conclusions: This study demonstrated that emotional status and DM are factors associated with impaired LV systolic function in patients with stable CAD.
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Keywords

left ventricular systolic function; coronary artery disease; depression; anxiety

About this article
Title

Relationship between psychosocial status, diabetes mellitus, and left ventricular systolic function in patients with stable multivessel coronary artery disease

Journal

Cardiology Journal

Issue

Vol 19, No 3 (2012)

Pages

249-255

Published online

2012-05-28

Bibliographic record

Cardiol J 2012;19(3):249-255.

Keywords

left ventricular systolic function
coronary artery disease
depression
anxiety

Authors

Orhan Dogdu
Mikail Yarlioglues
Mehmet Gungor Kaya
Idris Ardic
Mahmut Akpek
Omer Senarslan
Deniz Elcik
Omer Sahin
Erol Tulumen
Bekir Calapkorur
Nihat Kalay

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