open access

Vol 13, No 4 (2006): Folia Cardiologica
Case Reports
Published online: 2006-04-24
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Fungal endocarditis complicated by shock in the course of long-term permanent cardiac pacing

Wiesława Duszyńska, Grażyna Kübler, Joanna Moszczyńska-Stulin, Jarosław Janc, Andrzej Dumański, Anna Goździk, Andrzej Kübler
Folia Cardiol 2006;13(4):344-347.

open access

Vol 13, No 4 (2006): Folia Cardiologica
Case Reports
Published online: 2006-04-24

Abstract

The case is presented of a 52-year-old female patient who was diagnosed as having fungal endocarditis due to the Mucor species infection. The patient had had permanent cardiac pacing for 23 years. She was admitted to the hospital with symptoms of sepsis, and TTE revealed the development of vegetations on the pacemaker leads. Cardiac surgery with removal of the infected system was performed and a new pacemaker with an epicardial lead was implanted. After the surgery the patient’s clinical course was complicated by multiple organ dysfunction syndrome and septic shock, which was resistant to traditional treatment. Administration of human recombinant activated protein C (Xigris) improved organ function and enabled selective antifungal therapy to be continued. The patient was discharged from hospital 48 days later in a good condition.

Abstract

The case is presented of a 52-year-old female patient who was diagnosed as having fungal endocarditis due to the Mucor species infection. The patient had had permanent cardiac pacing for 23 years. She was admitted to the hospital with symptoms of sepsis, and TTE revealed the development of vegetations on the pacemaker leads. Cardiac surgery with removal of the infected system was performed and a new pacemaker with an epicardial lead was implanted. After the surgery the patient’s clinical course was complicated by multiple organ dysfunction syndrome and septic shock, which was resistant to traditional treatment. Administration of human recombinant activated protein C (Xigris) improved organ function and enabled selective antifungal therapy to be continued. The patient was discharged from hospital 48 days later in a good condition.
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Keywords

endocarditis; sepsis; mucormycosis; permanent cardiac pacing; activated protein C

About this article
Title

Fungal endocarditis complicated by shock in the course of long-term permanent cardiac pacing

Journal

Cardiology Journal

Issue

Vol 13, No 4 (2006): Folia Cardiologica

Pages

344-347

Published online

2006-04-24

Bibliographic record

Folia Cardiol 2006;13(4):344-347.

Keywords

endocarditis
sepsis
mucormycosis
permanent cardiac pacing
activated protein C

Authors

Wiesława Duszyńska
Grażyna Kübler
Joanna Moszczyńska-Stulin
Jarosław Janc
Andrzej Dumański
Anna Goździk
Andrzej Kübler

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